Evidence map›Paper›PMID 33829694›Full record

ArticleSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition2021

[Effects of Acrolein on the Proliferation of and

Cong-Min Li, Yang Liu, Li-Min Xu, Wei-Dong Wu, Bi-Jie Jiang

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Cong-Min LiDepartment of Occupational and Environmental Health, School of Public Health, Xinxiang Medical University, Xinxiang 453003, China.
Yang LiuDepartment of Histology and Embryology, School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang 453003, China.
Li-Min XuDepartment of Occupational and Environmental Health, School of Public Health, Xinxiang Medical University, Xinxiang 453003, China.
Wei-Dong WuDepartment of Occupational and Environmental Health, School of Public Health, Xinxiang Medical University, Xinxiang 453003, China.
Bi-Jie JiangDepartment of Occupational and Environmental Health, School of Public Health, Xinxiang Medical University, Xinxiang 453003, China.
Xinxiang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the effect of acrolein on the proliferation of pulmonary epithelial cells and its possible mechanism.

methodsTwo strains of pulmonary epithelial cells, A549 cells and MLE15 cells, were used as

resultsThe proliferation of A549 cells and MLE15 cells decreased significantly after being treated with 80 μmol/L acrolein for 30 min, and the expression of Per1 protein was also downregulated significantly (

conclusionAcrolein treatment resulted in the decreased proliferation of pulmonary epithelial cells and the Per1 expression in pulmonary epithelial cells. Although TGF-β addition did not reverse the reduction of cell proliferation after acrolein treatment, the Per1 expression levels were recovered to a certain extent compared to that in cells restored in medium without TGF-β after acrolein treatment.

Indexed as

AcroleinEpithelial CellsCell ProliferationGene ExpressionLungAcroleinAcroleinPer1Pulmonary epithelial cellsTransforming growth factor-β

Identifiers

PMID33829694
PMCPMC10408920
OpenAlexW3149197851

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.