ReviewMolecular neurobiology2021
Clinical and Pathophysiologic Spectrum of Neuro-COVID.
Review in Molecular neurobiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 48 citations in OpenAlex.
- Aggravating mechanisms from COVID-19.Virology journal · 2024Review
- Addressing Long COVID Sequelae and Neurocovid: Neuropsychological Scenarios and Neuroimaging Findings.Advances in experimental medicine and biology · 2024Review
- Recombinant SARS-CoV-2 Spike Protein and Its Receptor Binding Domain Stimulate Release of Different Pro-Inflammatory Mediators via Activation of Distinct Receptors on Human Microglia Cells.Molecular neurobiology · 2023Article
- Review
- Neuropsychological measures of post-COVID-19 cognitive status.Frontiers in psychology · 2023Article
- Opsoclonus Myoclonus Ataxia Syndrome Due to SARS-CoV-2.Neuro-ophthalmology (Aeolus Press) · 2023Review
- Neurovisual Manifestations in Children with Mild COVID-19: An Association to Remember.Neuro-ophthalmology (Aeolus Press) · 2023Article
- The role of Substance P in the defense line of the respiratory tract and neurological manifestations post COVID-19 infection.Frontiers in neurology · 2023Article
- No serological evidence for neuronal damage or reactive gliosis in neuro-COVID-19 patients with long-term persistent headache.Neurological research and practice · 2022Article
- COVID-19 Molecular Pathophysiology: Acetylation of Repurposing Drugs.International journal of molecular sciences · 2022Review
- Combining Deep Phenotyping of Serum Proteomics and Clinical Data via Machine Learning for COVID-19 Biomarker Discovery.International journal of molecular sciences · 2022Article
- Impact of mild COVID-19 on balance function in young adults, a prospective observational study.Scientific reports · 2022Observational
- Neurological effects of COVID-19 in infants and children.Developmental medicine and child neurology · 2022Review
- Pregnancy and neurologic complications of COVID-19: A scoping review.Acta neurologica Scandinavica · 2022Article
- Pathophysiology of SARS-CoV-2 associated ischemic stroke.Journal of medicine and life · 2022Article
- Neuropsychiatric disorders and COVID-19.The lancet. Psychiatry · 2021Article
- The SARS-CoV-2 Pandemic Does Not Absolve From Solid Medical Trade.Ochsner journal · 2021Article
- Secondary mechanisms by which SARS-CoV-2 affects the brain.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Though the lungs are predominantly affected in SARS-CoV-2-infected patients, extra-pulmonary manifestations can occur. Extra-pulmonary manifestations of the central and peripheral nervous system need to be recognised as they can strongly determine the outcome. This mini-review summarises and discusses previous and recent findings about neuro-COVID. The spectrum of central nervous system disease in COVID-19 patients is much broader than so far anticipated. Peripheral nerves and the skeletal muscle are less predominantly affected. In the vast majority of the cases, there is no direct attack of the virus towards vulnerable structures, which explains why various manifestations of the nervous system manifest favourably to immune suppression or immune modulation. Overall, the pathophysiology and clinical presentation of CNS/PNS involvement in COVID-19 is wider than believed. All patients with COVID-19 should be investigated by the neurologist for primary or secondary involvement of the CNS/PNS in the infection. neuro-COVID responds favourably to immune suppressants or immune modulation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.