Evidence map›Paper›PMID 33829316›Full record

ArticleJournal of cancer research and clinical oncology2021

Ground glass opacity featured lung adenocarcinoma in teenagers.

Haoxuan Wu, Yang Zhang, Hong Hu, Yuan Li, Xuxia Shen, Quan Liu, Shengping Wang, Haiquan Chen

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cancer research and clinical oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Over- and underscreening for lung cancer.Translational lung cancer research · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Primary lung cancer in children and adolescents.Journal of cancer research and clinical oncology · 2024
    Article
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Haoxuan Wu *Department of Thoracic Surgery and State Key Laboratory of Genetic Engineering, Fudan University Shanghai Cancer Center, 270 Dong-An Road, Shanghai, 200032, China.
Yang Zhang *Department of Thoracic Surgery and State Key Laboratory of Genetic Engineering, Fudan University Shanghai Cancer Center, 270 Dong-An Road, Shanghai, 200032, China.
Hong HuDepartment of Thoracic Surgery and State Key Laboratory of Genetic Engineering, Fudan University Shanghai Cancer Center, 270 Dong-An Road, Shanghai, 200032, China.
Yuan LiDepartment of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
Xuxia ShenDepartment of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
Quan LiuDepartment of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
Shengping WangDepartment of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
Haiquan ChenDepartment of Thoracic Surgery and State Key Laboratory of Genetic Engineering, Fudan University Shanghai Cancer Center, 270 Dong-An Road, Shanghai, 200032, China. hqchen1@yahoo.com.ORCID http://orcid.org/0000-0002-1305-971X
Shanghai Medical College of Fudan University · CN

Funding

National Natural Science Foundation of China 81930073Pilot Project of Fudan University IDF159034Shanghai Municipal Key Clinical Specialty Project SHSLCZDZK02104Shanghai Municipal Science and Technology Major Project 2017SHZDZX01Shanghai Municipal Science and Technology Major Project VBH1323001/026
6 · The paper itself

Abstract

introductionGround glass opacity (GGO) nodules were found incidentally by computed tomography (CT) scan in some teenagers, which turned out to be lung cancer. The purpose of this study is to summarize the characteristics of teenage patients with GGO featured lung adenocarcinoma.

methodsPatients aging from 13 to 20 who were incidentally diagnosed with lung cancer were reviewed between February 2015 to December 2020. The clinical, radiological and pathological characteristics were analyzed.

resultsTotally 12 patients were included. All of them were diagnosed as GGO featured lung cancer through CT scan, with no presenting symptom. The median surveillance before surgery was 5.5 months, and none of these GGO lesions enlarged or altered in the property during the surveillance. The mean tumor diameter was 0.93 ± 0.25 cm. Ten patients underwent wedge resection by video-assisted thoracoscopic surgery (VATS), 9 of which were minimally invasive adenocarcinoma (MIA) and 1 of which were invasive adenocarcinoma (IAC) in the pathological analysis. One patient underwent VATS left-upper sublobectomy, pathologically diagnosed as MIA and 1 patient underwent VATS left-upper lobectomy with systematic mediastinal lymphadenectomy, pathologically diagnosed as IAC. The median postoperative hospital stay was 3 days. All patients survived without recurrence during a median follow-up of 12.5 months.

conclusionsGGO nodules could be a sign of early-stage teenage lung adenocarcinoma. We proposed a screening strategy with long intervals based on a baseline CT scan for the teenage population, and a treatment strategy for diagnosed teenage patients.

Indexed as

Adenocarcinoma of LungAdolescentFemaleHumansIncidental FindingsLung NeoplasmsMaleYoung AdultAdenocarcinomaGround glass opacity nodulesScreeningTeenagerTreatment

Identifiers

PMID33829316
PMCPMC8026089
OpenAlexW3148593348

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.