ArticleThe Journal of antimicrobial chemotherapy2021
Characterization of Klebsiella pneumoniae complex isolates from pigs and humans in farms in Thailand: population genomic structure, antibiotic resistance and virulence genes.
Article in The Journal of antimicrobial chemotherapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 31 papers, 1 of them a synthesis that pooled it.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Pooled it
- Nationwide genomic surveillance of carbapenem- and colistin-resistant Klebsiella pneumoniae bloodstream isolates in Thailand (2020-2024).Scientific reports · 2026Article
- Circulation of ESBL-producingFrontiers in public health · 2026Article
- Antimicrobial Resistance, Virulence, and Genomic Characteristics ofTransboundary and emerging diseases · 2026Article
- Evolutionary Origins and Virulence Determinants of ST25 HypervirulentTransboundary and emerging diseases · 2026Article
- Carbohydrate competition by Enterobacteriaceae enhances colonization resistance to carbapenem-resistant hypervirulent K. pneumoniae.Microbiome · 2025Article
- A metabolic atlas of the Klebsiella pneumoniae species complex reveals lineage-specific metabolism and capacity for intra-species co-operation.PLoS biology · 2025Article
- Global trends of antimicrobial resistance and virulence of Klebsiella pneumoniae from different host sources.Communications medicine · 2025Article
- Genomic Characterization of Multidrug-Resistant and ESBL-ProducingMicroorganisms · 2025Article
- Biofilm Formation, Antibiotic Resistance, and Virulence Analysis of Human and Avian OriginVeterinary sciences · 2025Article
- A genome-wide One Health study of Klebsiella pneumoniae in Norway reveals overlapping populations but few recent transmission events across reservoirs.Genome medicine · 2025Article
- Prevalence and Virulence Profiles of Klebsiella pneumoniae Isolated From Different Animals.Veterinary medicine and science · 2025Article
- Virulence profile of carbapenem-resistantMicrobiology spectrum · 2025Article
- The multifaceted roles of phosphoethanolamine-modified lipopolysaccharides: from stress response and virulence to cationic antimicrobial resistance.Microbiology and molecular biology reviews : MMBR · 2024Review
- Genomic insights unveil the plasmid transfer mechanism and epidemiology of hypervirulent Klebsiella pneumoniae in Vietnam.Nature communications · 2024Article
- Genomic characterization of carbapenem and colistin-resistantFrontiers in veterinary science · 2024Article
- Clonal dissemination of highly virulentOne health (Amsterdam, Netherlands) · 2023Article
- Genomic features of Klebsiella isolates from artisanal ready-to-eat food production facilities.Scientific reports · 2023Article
- Highly conserved composite transposon harbouring aerobactinMicrobial genomics · 2023Article
- Carbapenemase-ProducingAntibiotics (Basel, Switzerland) · 2023Article
Corrections and comments
- Erratum issued
Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo define characteristics of Klebsiella pneumoniae complex (hereafter KP) isolates from healthy pigs, farm workers and their household members in Thailand.
methodsA total of 839 individual rectal swabs from pigs on 164 farms and 271 faecal samples of humans working on pig farms and persons living in the same household in Khon Kaen, Thailand were screened for gut colonization by KP. Genomic sequences were investigated for antibiotic resistance and virulence genes. Phylogenetic analyses were performed in addition to comparison with isolates from previous studies from Thailand.
resultsKP was detected in approximately 50% of pig and human samples. In total, 253 KP isolates were obtained: 39% from pigs, 34% from farmers and 26% from individuals living on the same farm but without animal contact. MLST revealed high genetic diversity with 196 different STs distributed over four phylogroups (Kp1 to Kp4). Low prevalence of ESBL-KP (7.5%) and colistin-resistant KP (3.2%) was observed among pigs and humans. Remarkably, four convergent MDR and hypervirulent strains were observed: one from pigs (ST290) and three from humans [ST35, ST3415 (strain 90CP1), ST17 (strain 90CM2)]. Sharing of KP clones among pigs and humans was identified for some STs including ST4788, ST661, ST3541 and ST29.
conclusionsThe study indicated a low prevalence of ESBL and mcr genes among KP isolated from pigs and healthy humans in Thailand and suggested the possibility of zoonotic transmission for a subset of circulating KP clones.
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