Evidence map›Paper›PMID 33829130›Full record

ArticleOne health outlook2020

Extended-spectrum ß-lactamase-producing

Mabel Kamweli Aworh, Jacob Kwaga, Emmanuel Okolocha, Lyndy Harden, Dawn Hull, Rene S Hendriksen, Siddhartha Thakur

Open access · goldAbstract read
In one paragraph

Article in One health outlook, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 4 pooled it
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 4 syntheses or guidelines pooled it, 77 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Article
  7. Review
  8. Article
  9. Tracking ESBL-ProducingVeterinary sciences · 2026
    Article
  10. Article
  11. Article
  12. Presence of ResistantVeterinary sciences · 2025
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Mabel Kamweli AworhDepartment of Veterinary and Pest Control Services, Federal Ministry of Agriculture and Rural Development, Abuja, Nigeria.ORCID 0000-0003-4213-6929
Jacob KwagaDepartment of Veterinary Public Health and Preventive Medicine, Ahmadu Bello University, Zaria, Nigeria.
Emmanuel OkolochaDepartment of Veterinary Public Health and Preventive Medicine, Ahmadu Bello University, Zaria, Nigeria.
Lyndy HardenDepartment of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina USA.
Dawn HullDepartment of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina USA.
Rene S HendriksenWHO, FAO, EU Reference Laboratory for Antimicrobial Resistance, Technical University of Denmark, National Food Institute, Kgs. Lyngby, Denmark.
Siddhartha ThakurDepartment of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina USA.
Ahmadu Bello University · NGNorth Carolina State University · USTechnical University of Denmark · DK

Funding

Enhance the surveillance of foodborne bacterial pathogens isolated from food and environmental samples using whole genome sequencing (WGS) to prevent foodborne outbreaks and promote public healthU19FD007113 · FDA · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI THAKUR, SIDDHARTHA · 2020 to 2024
$1.1M
FDA HHS U19 FD007113
6 · The paper itself

Abstract

backgroundGlobally, chicken is known to be a reservoir for the spread of antimicrobial resistance genes to humans. In Nigeria, antimicrobial drugs are readily accessible for use in poultry production, either for preventive or therapeutic purposes. Extended-spectrum beta-lactamase-producing

methodsWe conducted a cross-sectional study among workers, chickens and poultry environment in selected farms/chicken markets in Abuja. Stool, faecal, and environmental samples were collected from apparently healthy workers, chickens, and farm/market environments from December 2018 to April 2019. Data were collected electronically using an open data kit (ODK) installed on a Smartphone. Antimicrobial resistance was determined using broth micro-dilution methods against a panel of 14 antimicrobial agents. We carried out the phenotypic and genotypic characterization of the isolates. Data were analyzed by computing frequencies, proportions and spearman's correlation (ρ).

resultsOf 429 samples, 26.8% (

conclusionsESBL-EC isolates were prevalent amongst apparently healthy individuals, chickens and the poultry farm/market environment in Abuja. It is important to educate healthcare workers that people in proximity with poultry are a high-risk group for faecal carriage of ESBL-EC, hence pose a higher risk to the general population for the spread of antimicrobial resistance.

Indexed as

Antimicrobial resistanceChickenEscherichia coliExtended-spectrum β-lactamases (ESBL)Nigeria

Identifiers

PMID33829130
PMCPMC7993457
OpenAlexW3031913255

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.