Evidence map›Paper›PMID 33829069›Full record

ArticleInternational journal of particle therapy2021

Tyvin Rich, Dongfeng Pan, Mahendra Chordia, Cynthia Keppel, David Beylin, Pavel Stepanov, Mira Jung, Dalong Pang, Scott Grindrod, Anatoly Dritschilo

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of particle therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Tyvin RichThe University of Virginia, Radiation Oncology and Diagnostic Radiology, Charlottesville, VA, USA.
Dongfeng PanThe University of Virginia, Radiology and Medical Imaging, Charlottesville, VA, USA.
Mahendra ChordiaThe University of Virginia, Radiology and Medical Imaging, Charlottesville, VA, USA.
Cynthia KeppelHampton University Proton Therapy Institute, Hampton, VA, USA.
David BeylinBrain Biosciences, Inc, Rockville, MD, USA.
Pavel StepanovBrain Biosciences, Inc, Rockville, MD, USA.
Mira JungGeorgetown University, Radiation Medicine, Washington, DC, USA.
Dalong PangGeorgetown University, Radiation Medicine, Washington, DC, USA.
Scott GrindrodShuttle Pharmaceuticals, Inc, Rockville, MD, USA.
Anatoly DritschiloGeorgetown University, Radiation Medicine, Washington, DC, USA.
Shuttle Pharmaceuticals (United States) · USGeorgetown University · USUniversity of Virginia · USHampton University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeProton therapy precisely delivers radiation to cancers to cause damaging strand breaks to cellular DNA, kill malignant cells, and stop tumor growth. Therapeutic protons also generate short-lived activated nuclei of carbon, oxygen, and nitrogen atoms in patients as a result of atomic transmutations that are imaged by positron emission tomography (PET). We hypothesized that the transition of MATERIALS AND

methodsReported here is a feasibility study with a therapeutic proton beam used to irradiate H

resultsThe

conclusionsThese data support the idea of therapeutic transmutation in vitro as a biochemical consequence of proton activation of

Indexed as

nucleosideoxygen-18positron emission tomography (PET)proton therapytheranostic

Identifiers

PMID33829069
PMCPMC8019575
OpenAlexW3137439670

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.