Evidence map›Paper›PMID 33829039›Full record

ArticleFrontiers in molecular biosciences2021

Role of Electrostatic Hotspots in the Selectivity of Complement Control Proteins Toward Human and Bovine Complement Inhibition.

Yogesh B Narkhede, Avneesh K Gautam, Rohaine V Hsu, Wilson Rodriguez, Nehemiah T Zewde, Reed E S Harrison, Pablo R Arantes, Zied Gaieb, Ronald D Gorham, Chris Kieslich and 3 more

Abstract read
In one paragraph

Article in Frontiers in molecular biosciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yogesh B NarkhedeDepartment of Bioengineering, University of California, Riverside, CA.
Avneesh K GautamNational Centre for Cell Science, Pune University Campus, Ganeshkhind, India.
Rohaine V HsuDepartment of Bioengineering, University of California, Riverside, CA.
Wilson RodriguezDepartment of Bioengineering, University of California, Riverside, CA.
Nehemiah T ZewdeDepartment of Bioengineering, University of California, Riverside, CA.
Reed E S HarrisonDepartment of Bioengineering, University of California, Riverside, CA.
Pablo R ArantesDepartment of Bioengineering, University of California, Riverside, CA.
Zied GaiebDepartment of Bioengineering, University of California, Riverside, CA.
Ronald D GorhamDepartment of Bioengineering, University of California, Riverside, CA.
Chris KieslichDepartment of Bioengineering, University of California, Riverside, CA.
Dimitrios MorikisDepartment of Bioengineering, University of California, Riverside, CA.
Arvind SahuNational Centre for Cell Science, Pune University Campus, Ganeshkhind, India.
Giulia PalermoDepartment of Bioengineering, University of California, Riverside, CA.

Funding

Salk Institute Cancer Training GrantT32CA009370 · NCI · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI Diana Clare Hargreaves, Jan Karlseder · 1986 to 2026
$8.6M
NCI NIH HHS T32 CA009370
6 · The paper itself

Abstract

Poxviruses are dangerous pathogens, which can cause fatal infection in unvaccinated individuals. The causative agent of smallpox in humans,

Indexed as

Complement cofactor activityComputational modelingSPICEVariola (smallpox) virusVCP

Identifiers

PMID33829039
PMCPMC8020814

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.