Evidence map›Paper›PMID 33828985›Full record

ReviewFrontiers in oncology2021

Exosomes and Their Role in Cancer Progression.

Yang Liu, Ke Shi, Yong Chen, Xianrui Wu, Zheng Chen, Ke Cao, Yongguang Tao, Xiang Chen, Junlin Liao, Jianda Zhou

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

  1. Review
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  5. Article
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  8. Review
  9. Article
  10. Article
  11. Review
  12. The epidermal integrin-mediated secretome regulates the skin microenvironment during tumorigenesis and repair.Matrix biology : journal of the International Society for Matrix Biology · 2024
    Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. The Landscape of Exosomes Biogenesis to Clinical Applications.International journal of nanomedicine · 2024
    Review
  18. Exosomes as Novel Diagnostic Biomarkers and Therapeutic Tools in Gliomas.International journal of molecular sciences · 2023
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yang LiuDepartments of Plastic and Reconstructive Surgery, The Third Xiangya Hospital, Central South University, Changsha, China.
Ke ShiDepartments of Plastic and Reconstructive Surgery, The Third Xiangya Hospital, Central South University, Changsha, China.
Yong ChenDepartment of Dermatology, The First Hospital of Changsha, Changsha, China.
Xianrui WuDepartments of Plastic and Reconstructive Surgery, The Third Xiangya Hospital, Central South University, Changsha, China.
Zheng ChenDepartments of Plastic and Reconstructive Surgery, The Third Xiangya Hospital, Central South University, Changsha, China.
Ke CaoDepartment of Oncology, The Third Xiangya Hospital, Central South University, Changsha, China.
Yongguang TaoKey Laboratory of Carcinogenesis, Ministry of Education, Cancer Research Institute, School of Basic Medicine, Central South University, Changsha, China.
Xiang ChenDepartment of Dermatology of Xiangya Hospital, Central South University, Changsha, China.
Junlin LiaoDepartments of Medical Cosmetology, The First Affiliated Hospital, University of South China, Hengyang, China.
Jianda ZhouDepartments of Plastic and Reconstructive Surgery, The Third Xiangya Hospital, Central South University, Changsha, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exosomes from extracellular vesicles can activate or inhibit various signaling pathways by transporting proteins, lipids, nucleic acids and other substances to recipient cells. In addition, exosomes are considered to be involved in the development and progression of tumors from different tissue sources in numerous ways, including remodeling of the tumor microenvironment, promoting angiogenesis, metastasis, and invasion, and regulating the immune escape of tumor cells. However, the precise molecular mechanisms by which exosomes participate in these different processes remains unclear. In this review, we describe the research progress of tumor cell-derived exosomes in cancer progression. We also discuss the prospects of the application of exosomes combined with nanoengineered chemotherapeutic drugs in the treatment of cancer.

Indexed as

angiogenesiscancer treatmentEMT - epithelial to mesenchymal transformationexosomesimmune regulationtumor microenvironment

Identifiers

PMID33828985
PMCPMC8020998

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.