Evidence map›Paper›PMID 33828964›Full record

ArticleImaging science in dentistry2021

CBCT imaging and histopathological characteristics of osteoradionecrosis and medication-related osteonecrosis of the jaw.

Ichiro Ogura, Yoshiyuki Minami, Junya Ono, Yoriaki Kanri, Yasuo Okada, Kensuke Igarashi, Maiko Haga-Tsujimura, Ken Nakahara, Eizaburo Kobayashi

Abstract read
In one paragraph

Article in Imaging science in dentistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ichiro OguraDepartment of Oral and Maxillofacial Radiology, The Nippon Dental University School of Life Dentistry at Niigata, Niigata, Japan.ORCID https://orcid.org/0000-0002-9169-8429
Yoshiyuki MinamiDepartment of Oral and Maxillofacial Radiology, The Nippon Dental University School of Life Dentistry at Niigata, Niigata, Japan.ORCID https://orcid.org/0000-0003-0832-4619
Junya OnoDepartment of Pathology, The Nippon Dental University School of Life Dentistry at Niigata, Niigata, Japan.ORCID https://orcid.org/0000-0002-2133-6932
Yoriaki KanriDepartment of Pathology, The Nippon Dental University School of Life Dentistry at Niigata, Niigata, Japan.ORCID https://orcid.org/0000-0002-9124-2077
Yasuo OkadaDepartment of Pathology, The Nippon Dental University School of Life Dentistry at Niigata, Niigata, Japan.ORCID https://orcid.org/0000-0001-5068-5990
Kensuke IgarashiDepartment of Dental Materials Science, The Nippon Dental University School of Life Dentistry at Niigata, Niigata, Japan.ORCID https://orcid.org/0000-0001-6612-6982
Maiko Haga-TsujimuraDepartment of Histology, The Nippon Dental University School of Life Dentistry at Niigata, Niigata, Japan.ORCID https://orcid.org/0000-0001-8985-3015
Ken NakaharaAdvanced Research Center, The Nippon Dental University School of Life Dentistry at Niigata, Niigata, Japan.ORCID https://orcid.org/0000-0002-4992-7582
Eizaburo KobayashiDepartment of Oral and Maxillofacial Surgery, The Nippon Dental University School of Life Dentistry at Niigata, Niigata, Japan.ORCID https://orcid.org/0000-0002-5356-7671

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study was to evaluate the cone-beam computed tomographic (CBCT) imaging and histopathological characteristics of osteoradionecrosis (ORN) and medication-related osteonecrosis of the jaw (MRONJ). MATERIALS AND

methodsTen surgical specimens from segmental mandibulectomy (3 ORN and 7 MRONJ) were analyzed using CBCT. The CBCT parameters were as follows: high-resolution mode (tube voltage, 90.0 kV; tube current, 4.00 mA; rotation time, 16.8 s; field of view, 56 mm×56 mm; thickness, 0.099 mm). Histopathological characteristics were evaluated using histological slides of the surgical specimens. The Pearson chi-square test was used to compare ORN and MRONJ in terms of CBCT findings (internal texture, sequestrum, periosteal reaction and cortical perforation) and histopathological characteristics (necrotic bone, inflammatory cells, reactive bone formation, bacteria,

resultsMRONJ showed periosteal reaction on CBCT more frequently than ORN (7 of 7 [100%] vs. 0 of 3 [0%],

conclusionThis study evaluated the CBCT imaging and histopathological characteristics of ORN and MRONJ, and the findings suggest that CBCT could be useful for the evaluation of ORN and MRONJ.

Indexed as

Bisphosphonate-Associated Osteonecrosis of the JawCone-Beam Computed TomographyOsteoradionecrosis

Identifiers

PMID33828964
PMCPMC8007393

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.