Evidence map›Paper›PMID 33828607›Full record

ArticleDrugs in context2021

The effect of azoximer bromide (Polyoxidonium®) in patients hospitalized with coronavirus disease (COVID-19): an open-label, multicentre, interventional clinical study.

Sergey V Efimov, Natallia V Matsiyeuskaya, Olga V Boytsova, Lyudmila Yu Akhieva, Elena I Kvasova, Francisco Harrison, Yulia S Karpova, Anton Tikhonov, Nadezhda F Khomyakova, Tim Hardman and 1 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Drugs in context, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Sergey V EfimovState-Funded Healthcare Institution 'Emergency Hospital' of Ministry of Health of Chuvash Republic, Chuvash Republic, Cheboksary, Russia.ORCID https://orcid.org/0000-0001-6563-650X
Natallia V MatsiyeuskayaHealthcare Institution 'Grodno Regional Infectious Clinical Hospital', Grodno, Belarus.ORCID https://orcid.org/0000-0001-8492-6377
Olga V BoytsovaState-Funded Healthcare Institution 'Infectious Disease Hospital No.3' of Ministry of Health of Krasnodar Krai, Krasnodar Krai, Novorossiysk, Russia.ORCID https://orcid.org/0000-0001-5166-1165
Lyudmila Yu AkhievaState-Funded Institution of Mari El Republic 'Ioshkar-Ola City Hospital', Mari El Republic, Ioshkar Ola, Russia.ORCID https://orcid.org/0000-0002-2280-3299
Elena I KvasovaState-Funded Healthcare Institution of Voronezh Region 'Novaya Usman District Hospital', Voronezh Region, Novaya Usman, Russia.
Francisco HarrisonIDEA Regulatory, London, UK.
Yulia S KarpovaNPO Petrovax Pharm LLC, Moscow, Russia.ORCID https://orcid.org/0000-0003-3253-4982
Anton TikhonovNPO Petrovax Pharm LLC, Moscow, Russia.ORCID https://orcid.org/0000-0002-4671-0812
Nadezhda F KhomyakovaNPO Petrovax Pharm LLC, Moscow, Russia.ORCID https://orcid.org/0000-0002-9111-3144
Tim HardmanNiche Science & Technology, Richmond, UK.ORCID https://orcid.org/0000-0002-1417-9019
Jean-François RossiInstitut Sainte Catherine, Avignon, France.ORCID https://orcid.org/0000-0003-1562-8848
Institut Sainte Catherine · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A clinical need for aetiotropic coronavirus disease (COVID-19) treatments is required. The immune modulator azoximer bromide (AZB; Polyoxidonium®) is indicated in Russia for use against acute viral infections and during remission. In this study, adults hospitalized with COVID-19 (

Indexed as

azoximer bromide (Polyoxidonium®)COVID-19inflammationobservational study

Identifiers

PMID33828607
PMCPMC8007208
OpenAlexW3137386017

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.