Evidence map›Paper›PMID 33828558›Full record

ArticleFrontiers in immunology2021

Functional and Activation Profiles of Mucosal-Associated Invariant T Cells in Patients With Tuberculosis and HIV in a High Endemic Setting.

Avuyonke Balfour, Charlotte Schutz, Rene Goliath, Katalin A Wilkinson, Sumaya Sayed, Bianca Sossen, Jean-Paul Kanyik, Amy Ward, Rhandzu Ndzhukule, Anele Gela and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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  6. Relevant mechanisms of MAIT cells involved in the pathogenesis of periodontitis.Frontiers in cellular and infection microbiology · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Avuyonke BalfourDepartment of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Charlotte SchutzDepartment of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Rene GoliathWellcome Centre for Infectious Diseases Research in Africa (CIDRI-Africa), Faculty of Health Sciences, Institute of Infectious Disease and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.
Katalin A WilkinsonWellcome Centre for Infectious Diseases Research in Africa (CIDRI-Africa), Faculty of Health Sciences, Institute of Infectious Disease and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.
Sumaya SayedWellcome Centre for Infectious Diseases Research in Africa (CIDRI-Africa), Faculty of Health Sciences, Institute of Infectious Disease and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.
Bianca SossenDepartment of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Jean-Paul KanyikWellcome Centre for Infectious Diseases Research in Africa (CIDRI-Africa), Faculty of Health Sciences, Institute of Infectious Disease and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.
Amy WardWellcome Centre for Infectious Diseases Research in Africa (CIDRI-Africa), Faculty of Health Sciences, Institute of Infectious Disease and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.
Rhandzu NdzhukuleWellcome Centre for Infectious Diseases Research in Africa (CIDRI-Africa), Faculty of Health Sciences, Institute of Infectious Disease and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.
Anele GelaSouth African Tuberculosis Vaccine Initiative, Faculty of Health Sciences, Institute of Infectious Disease and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.
David M LewinsohnDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Oregon Health and Science University, Portland, OR, United States.
Deborah A LewinsohnDivision of Infectious Diseases, Department of Paediatrics, Oregon Health and Science University, Portland, OR, United States.
Graeme MeintjesDepartment of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Muki SheyDepartment of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
University of Cape Town · ZAOregon Health & Science University · USWellcome Centre for Infectious Diseases Research in Africa · ZAThe Francis Crick Institute · GB

Funding

Lung Resident, MR1-Restricted T Cells: Association with Differential Outcomes Following Exposure to M. TuberculosisR01AI134790 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI LEWINSOHN, DAVID M., WALZL, GERHARD · 2018 to 2022
$3.3M
HIV-associated Tuberculosis Training Program (HATTP)D43TW010559 · FIC · UNIVERSITY OF CAPE TOWN · PI Graeme Ayton Meintjes · 2017 to 2026
$3.0M
Memory, Phenotype, and Function of TB-reactive Human MR1 Restricted T cellsR01AI129980 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI LEWINSOHN, DAVID M., LEWINSOHN, DEBORAH A. · 2019 to 2022
$2.4M
FIC NIH HHS D43 TW010559NIAID NIH HHS R01 AI129980NIAID NIH HHS R01 AI134790Wellcome TrustWellcome Trust 098316Wellcome Trust 203135/Z/16/ZWellcome Trust 211360/Z/18/ZWellcome Trust 214321/Z/18/Z
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Endemic DiseasesAdultAIDS-Related Opportunistic InfectionsAntitubercular AgentsCase-Control StudiesCross-Sectional StudiesFemaleFlow CytometryHIV-1HLA-DR AntigensHumansImmunity, MucosalInterferon-gammaLatent InfectionLymphocyte ActivationLymphocyte CountAntitubercular AgentsHLA-DR AntigensIFNG protein, humanInterferon-gammahuman immunodeficiency virusMAIT activationMAIT cellMAIT cell functiontuberculosis

Identifiers

PMID33828558
PMCPMC8019701
OpenAlexW3138967066

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.