Evidence map›Paper›PMID 33828486›Full record

ReviewFrontiers in physiology2021

Acetylation Modification During Autophagy and Vascular Aging.

Jiaxing Sun, Shi Tai, Liang Tang, Hui Yang, Mingxian Chen, Yichao Xiao, Xuping Li, Zhaowei Zhu, Shenghua Zhou

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jiaxing SunDepartment of Cardiology, The Second Xiangya Hospital of Central South University, Changsha, China.
Shi TaiDepartment of Cardiology, The Second Xiangya Hospital of Central South University, Changsha, China.
Liang TangDepartment of Cardiology, The Second Xiangya Hospital of Central South University, Changsha, China.
Hui YangDepartment of Cardiology, The Second Xiangya Hospital of Central South University, Changsha, China.
Mingxian ChenDepartment of Cardiology, The Second Xiangya Hospital of Central South University, Changsha, China.
Yichao XiaoDepartment of Cardiology, The Second Xiangya Hospital of Central South University, Changsha, China.
Xuping LiDepartment of Cardiology, The Second Xiangya Hospital of Central South University, Changsha, China.
Zhaowei ZhuDepartment of Cardiology, The Second Xiangya Hospital of Central South University, Changsha, China.
Shenghua ZhouDepartment of Cardiology, The Second Xiangya Hospital of Central South University, Changsha, China.
Second Xiangya Hospital of Central South University · CNCentral South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vascular aging plays a pivotal role in the morbidity and mortality of elderly people. Decrease in autophagy leads to acceleration of vascular aging, while increase in autophagy leads to deceleration of vascular aging. And emerging evidence indicates that acetylation plays an important role in autophagy regulation; therefore, recent research has focused on an in-depth analysis of the mechanisms underlying this regulation. In this review, current knowledge on the role of acetylation of autophagy-related proteins and the mechanisms by which acetylation including non-autophagy-related acetylation and autophagy related acetylation regulate vascular aging have been discussed. We conclude that the occurrence of acetylation modification during autophagy is a fundamental mechanism underlying autophagy regulation and provides promising targets to retard vascular aging.

Indexed as

acetylationautophagyFOXO1SIRT1vascular aging

Identifiers

PMID33828486
PMCPMC8019697
OpenAlexW3137228036

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.