Evidence map›Paper›PMID 33828480›Full record

ArticleFrontiers in pharmacology2021

Osthole Attenuates Macrophage Activation in Experimental Asthma by Inhibitingthe NF-ĸB/MIF Signaling Pathway.

Ruyi Li, Peng Song, Guofang Tang, Jianghong Wei, Lizong Rao, Libing Ma, Ming Jiang, Jianwei Huang, Qing Xu, Jingjie Wu and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Osthole attenuates asthma-induced airway epithelial cell apoptosis and inflammation by suppressing TSLP/NF-κB-mediated inhibition of Th2 differentiation.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2024
    Article
  4. Vasorelaxant and Blood Pressure-Lowering Effects ofInternational journal of molecular sciences · 2024
    Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 1 country.

Ruyi LiKey Laboratory of National Clinical Research Center for Respiratory Disease, Department of Respiratory and Critical Care Medicine, Xiangya Hospital, Central South University, Changsha, China.
Peng SongKey Laboratory of Prevention and Treatment for Chronic Diseases by Traditional Chinese Medicine, Affiliated Hospital of Gansu University of Chinese Medicine, Lanzhou, China.
Guofang TangDepartment of Respiratory and Critical Care Medicine, Affiliated Hospital of Guilin Medical University, Guilin, China.
Jianghong WeiDepartment of Respiratory and Critical Care Medicine, Affiliated Hospital of Guilin Medical University, Guilin, China.
Lizong RaoDepartment of Respiratory and Critical Care Medicine, Affiliated Hospital of Guilin Medical University, Guilin, China.
Libing MaDepartment of Respiratory and Critical Care Medicine, Affiliated Hospital of Guilin Medical University, Guilin, China.
Ming JiangDepartment of Respiratory and Critical Care Medicine, Affiliated Hospital of Guilin Medical University, Guilin, China.
Jianwei HuangDepartment of Respiratory and Critical Care Medicine, Affiliated Hospital of Guilin Medical University, Guilin, China.
Qing XuDepartment of Respiratory and Critical Care Medicine, Affiliated Hospital of Guilin Medical University, Guilin, China.
Jingjie WuDepartment of Respiratory and Critical Care Medicine, Affiliated Hospital of Guilin Medical University, Guilin, China.
Qian LvDepartment of Respiratory and Critical Care Medicine, Affiliated Hospital of Guilin Medical University, Guilin, China.
Dong YaoLaboratory of Pulmonary Diseases, Guilin Medical University, Guilin, China.
Bo XiaoLaboratory of Pulmonary Diseases, Guilin Medical University, Guilin, China.
Haiming HuangLaboratory of Pulmonary Diseases, Guilin Medical University, Guilin, China.
Liping LeiLaboratory of Pulmonary Diseases, Guilin Medical University, Guilin, China.
Juntao FengKey Laboratory of National Clinical Research Center for Respiratory Disease, Department of Respiratory and Critical Care Medicine, Xiangya Hospital, Central South University, Changsha, China.
Biwen MoDepartment of Respiratory and Critical Care Medicine, Affiliated Hospital of Guilin Medical University, Guilin, China.
Guilin Medical University · CNCentral South University · CNShanghai University of Traditional Chinese Medicine · CNXiangya Hospital Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inhibition of activated macrophages is an alternative therapeutic strategy for asthma. We investigated whether a coumarin compound, osthole, isolated from

Indexed as

asthmamacrophagesMIF 46NF-ĸBosthole

Identifiers

PMID33828480
PMCPMC8020258
OpenAlexW3138694831

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.