ArticleFrontiers in human neuroscience2021
Brain Entropy During Aging Through a Free Energy Principle Approach.
Article in Frontiers in human neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Neural correlates of psychodynamic and non-psychodynamic therapies in different clinical populations through fMRI: A meta-analysis and systematic review.Frontiers in human neuroscience · 2022Pooled it
- Entropy of the resting state cortex in epilepsy.Biomedical physics & engineering express · 2026Article
- The entropic brain today.Brain : a journal of neurology · 2026Review
- Same ages, different stages: Pubertal development in 9- and 10-year olds is associated with entropy of fMRI signals.Developmental cognitive neuroscience · 2026Article
- Transcriptome profiling of neurexin- and neuroligin-deficient Caenorhabditis elegans reveals pathways underlying developmental and behavioral dysfunction.Research square · 2026Article
- Aberrant Brain Entropy in Alzheimer's Disease: Evidence From a Resting-State fMRI Study.Brain and behavior · 2026Article
- Task-specific dynamical entropy variations in EEG as a biomarker for Parkinson's disease progression.GeroScience · 2026Article
- Distinguishing early from late mild cognitive impairment: a multi-level analysis of regional morphometry and KLS-derived network topology.Frontiers in aging neuroscience · 2026Article
- Functional transition rate of the default mode network is associated with self-reported resilience.NeuroImage · 2025Article
- Infra-slow scale-free dynamics modulate the connection of neural and behavioral variability during attention.Communications biology · 2025Article
- Cognitive Control Difficulties Differentiate Callous-Unemotional Traits from Conduct Problems: A Pre-Registered Double-Blind Randomized Controlled Trial Analysis.Child psychiatry and human development · 2025Article
- Structured Dynamics in the Algorithmic Agent.Entropy (Basel, Switzerland) · 2025Article
- Rewiring the aging brain: exergaming modulates brain complexity in older adults.Frontiers in aging neuroscience · 2025Article
- Older is order: entropy reduction in cortical spontaneous activity marks healthy aging.BMC neuroscience · 2024Article
- Towards a neurodevelopmental cognitive perspective of temporal processing.Communications biology · 2024Review
- The brain entropy dynamics in resting state.Frontiers in neuroscience · 2024Article
- Dissociable Effects of Alzheimer's Disease-Related Cognitive Dysfunction and Aging on Functional Brain Network Segregation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Fatigue as Mediator Factor in PTSD-Symptoms after Allogeneic Hematopoietic Stem Cell Transplantation.Journal of clinical medicine · 2023Article
- Olfaction and Anxiety Are Differently Associated in Men and Women in Cognitive Physiological and Pathological Aging.Journal of clinical medicine · 2023Article
- Analytic Background in the Neuroscience of the Potential Project "Hippocrates".Brain sciences · 2022Review
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4 authors.
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Abstract
Neural complexity and brain entropy (BEN) have gained greater interest in recent years. The dynamics of neural signals and their relations with information processing continue to be investigated through different measures in a variety of noteworthy studies. The BEN of spontaneous neural activity decreases during states of reduced consciousness. This evidence has been showed in primary consciousness states, such as psychedelic states, under the name of "the entropic brain hypothesis." In this manuscript we propose an extension of this hypothesis to physiological and pathological aging. We review this particular facet of the complexity of the brain, mentioning studies that have investigated BEN in primary consciousness states, and extending this view to the field of neuroaging with a focus on resting-state functional Magnetic Resonance Imaging. We first introduce historic and conceptual ideas about entropy and neural complexity, treating the mindbrain as a complex nonlinear dynamic adaptive system, in light of the free energy principle. Then, we review the studies in this field, analyzing the idea that the aim of the neurocognitive system is to maintain a dynamic state of balance between order and chaos, both in terms of dynamics of neural signals and functional connectivity. In our exploration we will review studies both on acute psychedelic states and more chronic psychotic states and traits, such as those in schizophrenia, in order to show the increase of entropy in those states. Then we extend our exploration to physiological and pathological aging, where BEN is reduced. Finally, we propose an interpretation of these results, defining a general trend of BEN in primary states and cognitive aging.
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