Evidence map›Paper›PMID 33828470›Full record

ArticleFrontiers in human neuroscience2021

C-Gait for Detecting Freezing of Gait in the Early to Middle Stages of Parkinson's Disease: A Model Prediction Study.

Zi-Yan Chen, Hong-Jiao Yan, Lin Qi, Qiao-Xia Zhen, Cui Liu, Ping Wang, Yong-Hong Liu, Rui-Dan Wang, Yan-Jun Liu, Jin-Ping Fang and 5 more

Registry-linked trialAbstract read
In one paragraph

Article in Frontiers in human neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05902065 (Biomarkers of Rehabilitation Outcome in Patients With Parkinson's Disease), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05902065 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Biomarkers of Rehabilitation Outcome in Patients With Parkinson's Disease: Effect of a Customized Protocol on Treadmill Training With and Without Augmented Virtual Reality Application, a Randomized Controlled Trial

TypeinterventionalSponsorUniversity of FlorenceRan2022 to 2023Enrolled60ConditionsParkinson Disease, Gait, Festinating, Fall Due to Loss of Equilibrium, Gait, UnsteadyArmsAVR Treadmill training with C-Mill, Conventional Treadmill training with C-Mill
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Zi-Yan ChenBeijing Rehabilitation Hospital, Capital Medical University, Beijing, China.
Hong-Jiao YanBeijing Rehabilitation Hospital, Capital Medical University, Beijing, China.
Lin QiBeijing Rehabilitation Hospital, Capital Medical University, Beijing, China.
Qiao-Xia ZhenBeijing Rehabilitation Hospital, Capital Medical University, Beijing, China.
Cui LiuBeijing Rehabilitation Hospital, Capital Medical University, Beijing, China.
Ping WangBeijing Rehabilitation Hospital, Capital Medical University, Beijing, China.
Yong-Hong LiuBeijing Rehabilitation Hospital, Capital Medical University, Beijing, China.
Rui-Dan WangBeijing Rehabilitation Hospital, Capital Medical University, Beijing, China.
Yan-Jun LiuBeijing Rehabilitation Hospital, Capital Medical University, Beijing, China.
Jin-Ping FangBeijing Rehabilitation Hospital, Capital Medical University, Beijing, China.
Yuan SuBeijing Rehabilitation Hospital, Capital Medical University, Beijing, China.
Xiao-Yan YanPeking University Clinical Research Institute, Beijing, China.
Ai-Xian LiuBeijing Rehabilitation Hospital, Capital Medical University, Beijing, China.
Jianing XiBeijing Rehabilitation Hospital, Capital Medical University, Beijing, China.
Boyan FangBeijing Rehabilitation Hospital, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveEfficient methods for assessing walking adaptability in individuals with Parkinson's disease (PD) are urgently needed. Therefore, this study aimed to assess C-Gait for detecting freezing of gait (FOG) in patients with early- to middle-stage PD.

methodPeople with PD (PWP) diagnosis (Hoehn and Yahr stages 1-3) were recruited from April 2019 to November 2019 in Beijing Rehabilitation Hospital. The participants performed six items of walking adaptability on an instrumented treadmill augmented with visual targets and obstacles (C-Mill). The patient's walking adaptability was evaluated by C-Gait assessment and traditional walking tests, and FOG-related indexes were collected as outcome measures. Two discriminant models were established by stepwise discriminant analysis; area under the receiver operating characteristic (ROC) curve (AUC) was used to validate the models.

resultIn total, 53 patients were included in this study. Most C-Gait assessment items had no or low correlations with traditional walking tests. The obstacle avoidance (

conclusionC-gait assessment could provide additional value to the traditional walking tests for PD. Gait adaptability assessment, as measured by C-Gait, may be able to help identify freezers in a PD population.

Indexed as

C-Gait assessmentfreezing of gaitParkinson’s diseaserehabilitationwalking adaptability

Identifiers

PMID33828470
PMCPMC8019899

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.