Evidence map›Paper›PMID 33828381›Full record

ArticleJournal of pharmacy & bioallied sciences2020

Time to Treatment Initiation and Retrospective Analysis of Antiretroviral Therapy Outcomes among HIV-positive Methadone Maintenance Therapy Clients in Primary Health-care Centers, Kuantan, Pahang.

Aida Roziana Ramlan, Nor Ilyani Mohamed Nazar, Afidalina Tumian, Norny Syafinaz Ab Rahman, Dzawani Mohamad, Mat Sharil Abdul Talib, Khairul Faizan M Zakaria, Muhammad Azzim Izuddin, Nadia Akmal Zainal Abidin, Syarifah Syafiqah T Syed Manso and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of pharmacy & bioallied sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Aida Roziana RamlanKulliyyah of Pharmacy, International Islamic University Malaysia, Kuantan, Pahang, Malaysia.
Nor Ilyani Mohamed NazarKulliyyah of Pharmacy, International Islamic University Malaysia, Kuantan, Pahang, Malaysia.
Afidalina TumianKulliyyah of Engineering, International Islamic University Malaysia, Gombak, Selangor, Malaysia.
Norny Syafinaz Ab RahmanKulliyyah of Pharmacy, International Islamic University Malaysia, Kuantan, Pahang, Malaysia.
Dzawani MohamadMedical Department, Hospital Tengku Ampuan Afzan, Ministry of Health Malaysia, Kuantan, Pahang, Malaysia.
Mat Sharil Abdul TalibPharmacy Unit, Kurnia Health Clinic, Kuantan, Pahang, Malaysia.
Khairul Faizan M ZakariaPharmacy Unit, Paya Besar Health Clinic, Kuantan, Pahang, Malaysia.
Muhammad Azzim IzuddinPharmacy Unit, Bandar Kuantan Health Clinic, Kuantan, Pahang, Malaysia.
Nadia Akmal Zainal AbidinPharmacy Unit, Bukit Goh Health Clinic, Kuantan, Pahang, Malaysia.
Syarifah Syafiqah T Syed MansoPharmacy Unit, Jaya Gading Health Clinic, Kuantan, Pahang, Malaysia.
Wan Nur Khairiyah Wan HassanPharmacy Unit, Beserah Health Clinic, Kuantan, Pahang, Malaysia.
International Islamic University Malaysia · MYHospital Tengku Ampuan Afzan · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMethadone maintenance therapy (MMT) program helped to improve access to antiretroviral therapy (ART) among people who inject drugs (PWID) with human immunodeficiency virus (HIV). However, the time to treatment initiation (TTI) and outcomes of ART intervention in this population have scarcely been analyzed.

objectivesThe aim of this study was to analyze the TTI and outcomes of ART among MMT clients in primary health-care centers in Kuantan, Pahang. MATERIALS AND

methodsThis was a retrospective evaluation of MMT clients from 2006 to 2019. The TTI was calculated from the day of MMT enrolment to ART initiation. The trends of CD4 counts and viral loads were descriptively evaluated. Cox proportional hazard model was used to analyze the survival and treatment retention rate.

resultsA total of 67 MMT clients from six primary health-care centers were HIV-positive, of which 37 clients were started on ART. The mean TTI of ART was 27 months. The clients who were given ART had a mean CD4 count of 119 cells/mm

conclusionThe TTI of ART was delayed in this population. MMT clients who were given ART have better CD4 and viral load outcomes, helped reduced death risk and showed higher retention rates in MMT program.

Indexed as

Antiretroviral therapy treatment outcomesHIV positivemethadone maintenance therapytime to treatment initiation

Identifiers

PMID33828381
PMCPMC8021067
OpenAlexW3095644706

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.