Evidence map›Paper›PMID 33828364›Full record

ArticleJournal of pharmacy & bioallied sciences2020

Screening of Electrospray-operating Parameters in the Production of Alginate-Royal Jelly Microbeads Using Factorial Design.

Mohd Rus Shaiqah, Haris Muhammad Salahuddin, Abu Yazid Anis Afiful Huda, Mohamad Izzuddin, Noor Ismadi Muhammad Nur Shafiq, Mohd Azlan Nur Hakimah, Rahman Siti Radziah, Abd Almonem Doolaanea, Adina Anugerah Budipratama

Open access · goldAbstract read
In one paragraph

Article in Journal of pharmacy & bioallied sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Mohd Rus ShaiqahDepartment of Pharmaceutical Technology, Kulliyyah of Pharmacy, International Islamic University Malaysia, Kuantan, Malaysia.
Haris Muhammad SalahuddinDepartment of Pharmaceutical Technology, Kulliyyah of Pharmacy, International Islamic University Malaysia, Kuantan, Malaysia.
Abu Yazid Anis Afiful HudaDepartment of Pharmaceutical Technology, Kulliyyah of Pharmacy, International Islamic University Malaysia, Kuantan, Malaysia.
Mohamad IzzuddinDepartment of Pharmaceutical Technology, Kulliyyah of Pharmacy, International Islamic University Malaysia, Kuantan, Malaysia.
Noor Ismadi Muhammad Nur ShafiqDepartment of Pharmaceutical Technology, Kulliyyah of Pharmacy, International Islamic University Malaysia, Kuantan, Malaysia.
Mohd Azlan Nur HakimahDepartment of Pharmaceutical Technology, Kulliyyah of Pharmacy, International Islamic University Malaysia, Kuantan, Malaysia.
Rahman Siti RadziahDepartment of Pharmaceutical Technology, Kulliyyah of Pharmacy, International Islamic University Malaysia, Kuantan, Malaysia.
Abd Almonem DoolaaneaDepartment of Pharmaceutical Technology, Kulliyyah of Pharmacy, International Islamic University Malaysia, Kuantan, Malaysia.
Adina Anugerah BudipratamaIKOP, Kuantan, Malaysia.
International Islamic University Malaysia · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRoyal jelly (RJ) has been consumed as food or as a supplement because of its high nutritional and medicinal values. A fresh harvested RJ is yellowish to whitish in color and contains proteins, free amino acids, lipids, vitamins, and sugar. Without proper storage conditions, such as at 4°C, the color of RJ changes to much darker yellow and produces a rancid smell. To prolong its shelf life, RJ is usually mixed with honey. Alginate, a natural and edible polymer derived from seaweed, is commonly used to encapsulate drugs and food due to its ability to form gels by reacting with divalent cations. However, there is a lack of research on the microencapsulation of RJ in alginate using electrospray. The electrospray technique has the advantage in producing consistent size and shape of alginate microbeads under optimum parameters.

aimThis research aimed to optimize electrospray-operating parameters in producing alginate-RJ microbeads. MATERIALS AND

methodsOptimization of alginate-RJ microbeads electrospray parameters was carried out using 2

resultsNozzle size is a significant parameter that influences the particle size. Flow rate is a significant parameter influencing the sphericity factor.

conclusionScreening of the electrospray-operating parameters paves the way in determining the significant parameters and their design space to produce consistent alginate-RJ microbeads.

Indexed as

Alginateelectrosprayfactorial designroyal jelly

Identifiers

PMID33828364
PMCPMC8021049
OpenAlexW2998566391

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.