Evidence map›Paper›PMID 33828249›Full record

ArticleNature ecology & evolution2021

A genome sequence from a modern human skull over 45,000 years old from Zlatý kůň in Czechia.

Kay Prüfer, Cosimo Posth, He Yu, Alexander Stoessel, Maria A Spyrou, Thibaut Deviese, Marco Mattonai, Erika Ribechini, Thomas Higham, Petr Velemínský and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Nature ecology & evolution, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
17.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 124 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 5 countries.

Kay Prüfer *Max Planck Institute for the Science of Human History, Jena, Germany. pruefer@eva.mpg.de.ORCID http://orcid.org/0000-0001-6242-3058
Cosimo Posth *Max Planck Institute for the Science of Human History, Jena, Germany. cosimo.posth@uni-tuebingen.de.ORCID http://orcid.org/0000-0002-8206-3907
He YuMax Planck Institute for the Science of Human History, Jena, Germany.ORCID http://orcid.org/0000-0003-1323-4730
Alexander StoesselMax Planck Institute for the Science of Human History, Jena, Germany.
Maria A SpyrouMax Planck Institute for the Science of Human History, Jena, Germany.ORCID http://orcid.org/0000-0002-3615-3936
Thibaut DevieseOxford Radiocarbon Accelerator Unit, Research Laboratory for Archaeology and the History of Art, School of Archaeology, University of Oxford, Oxford, UK.
Marco MattonaiDepartment of Chemistry and Industrial Chemistry, University of Pisa, Pisa, Italy.ORCID http://orcid.org/0000-0001-5874-1811
Erika RibechiniDepartment of Chemistry and Industrial Chemistry, University of Pisa, Pisa, Italy.ORCID http://orcid.org/0000-0002-4978-2782
Thomas HighamOxford Radiocarbon Accelerator Unit, Research Laboratory for Archaeology and the History of Art, School of Archaeology, University of Oxford, Oxford, UK.
Petr VelemínskýDepartment of Anthropology, National Museum, Prague, Czech Republic.
Jaroslav BrůžekDepartment of Anthropology and Human Genetics, Faculty of Science, Charles University, Prague, Czech Republic.ORCID http://orcid.org/0000-0002-2478-9662
Johannes KrauseMax Planck Institute for the Science of Human History, Jena, Germany. krause@eva.mpg.de.ORCID http://orcid.org/0000-0001-9144-3920
Max Planck Institute for Evolutionary Anthropology · DEMax Planck Institute for the Science of Human History · DEUniversity of Pisa · ITCentre National de la Recherche Scientifique · FRCharles University · CZNational Museum · CZUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Modern humans expanded into Eurasia more than 40,000 years ago following their dispersal out of Africa. These Eurasians carried ~2-3% Neanderthal ancestry in their genomes, originating from admixture with Neanderthals that took place sometime between 50,000 and 60,000 years ago, probably in the Middle East. In Europe, the modern human expansion preceded the disappearance of Neanderthals from the fossil record by 3,000-5,000 years. The genetic makeup of the first Europeans who colonized the continent more than 40,000 years ago remains poorly understood since few specimens have been studied. Here, we analyse a genome generated from the skull of a female individual from Zlatý kůň, Czechia. We found that she belonged to a population that appears to have contributed genetically neither to later Europeans nor to Asians. Her genome carries ~3% Neanderthal ancestry, similar to those of other Upper Palaeolithic hunter-gatherers. However, the lengths of the Neanderthal segments are longer than those observed in the currently oldest modern human genome of the ~45,000-year-old Ust'-Ishim individual from Siberia, suggesting that this individual from Zlatý kůň is one of the earliest Eurasian inhabitants following the expansion out of Africa.

Indexed as

SkullAfricaCzech RepublicEuropeFemaleHumansInfant, NewbornMiddle EastSiberia

Identifiers

PMID33828249
PMCPMC8175239
OpenAlexW3140287304

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.