ArticleScientific reports2021
A refined medium to enhance the antimicrobial activity of postbiotic produced by Lactiplantibacillus plantarum RS5.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Optimization of fermentation medium for advancing postbiotic antibacterial activity.AMB Express · 2026Article
- Non-targeted metabolomics and postbiotics survey of an Iranian Koupa cheese Lactiplantibacillus plantarum isolate.Scientific reports · 2026Article
- Investigation of the Effects of Postbiotics Obtained fromFoods (Basel, Switzerland) · 2026Article
- Postbiotics: Definitions, Manufacturing, Analytical Characterization, and Clinical Evidence for Human and Animal Health.Current microbiology · 2026Review
- Scaling Up Postbiotics Production: A Prospective Review of Processes and Health Benefits.Probiotics and antimicrobial proteins · 2026Review
- From Probiotics to Postbiotics-An Update on Their Biotherapeutic Potential and the Emerging Strategies in Human Health.International journal of molecular sciences · 2026Review
- Exploring the probiotic landscape in understanding postbiotics from indigenous bacteria isolated from the stool samples of a tribal population at Mulluvadi village, Tamil Nadu, India.Frontiers in pharmacology · 2026Article
- Emerging Nonthermal Technologies for the Production of Postbiotics.Comprehensive reviews in food science and food safety · 2025Review
- Postbiotics: an insightful review of the latest category in functional biotics.World journal of microbiology & biotechnology · 2025Review
- Microalgal and Cyanobacterial Biomasses Modified the Activity of Extracellular Products from Bacillus pumilus: An In Vitro and In Vivo Assessment.Probiotics and antimicrobial proteins · 2025Article
- Antimicrobial and prebiotic properties ofIranian journal of microbiology · 2025Article
- Antiprotozoal Effects ofPathogens (Basel, Switzerland) · 2025Article
- Transcriptional Analysis and Identification of a Peptidoglycan Hydrolase (PGH) and a Ribosomal Protein with Antimicrobial Activity Produced byInternational journal of molecular sciences · 2024Article
- Novel Liposome-Gel Formulations Containing a Next Generation Postbiotic: Characterization, Rheological, Stability, Release Kinetic, and In Vitro Antimicrobial Activity Studies.Gels (Basel, Switzerland) · 2024Article
- Different Combinations of Nitrogen and Carbon Sources Influence the Growth and Postbiotic Metabolite Characteristics ofFoods (Basel, Switzerland) · 2024Article
- Optimizing postbiotic production through solid-state fermentation withFrontiers in microbiology · 2023Article
- Evaluation ofPathogens (Basel, Switzerland) · 2022Article
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Authors and funding
6 authors.
Funding
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Abstract
Postbiotic RS5, produced by Lactiplantibacillus plantarum RS5, has been identified as a promising alternative feed supplement for various livestock. This study aimed to lower the production cost by enhancing the antimicrobial activity of the postbiotic RS5 by improving the culture density of L. plantarum RS5 and reducing the cost of growth medium. A combination of conventional and statistical-based approaches (Fractional Factorial Design and Central Composite Design of Response Surface Methodology) was employed to develop a refined medium for the enhancement of the antimicrobial activity of postbiotic RS5. A refined medium containing 20 g/L of glucose, 27.84 g/L of yeast extract, 5.75 g/L of sodium acetate, 1.12 g/L of Tween 80 and 0.05 g/L of manganese sulphate enhanced the antimicrobial activity of postbiotic RS5 by 108%. The cost of the production medium was reduced by 85% as compared to the commercially available de Man, Rogosa and Sharpe medium that is typically used for Lactobacillus cultivation. Hence, the refined medium has made the postbiotic RS5 more feasible and cost-effective to be adopted as a feed supplement for various livestock industries.
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