Evidence map›Paper›PMID 33827949›Full record

ArticleJournal of virology2021

TLR5-Mediated Reactivation of Quiescent Ranavirus FV3 in

Mrinal Samanta, Jinyeong Yim, Francisco De Jesús Andino, Matthieu Paiola, Jacques Robert

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The amphibian immune system.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Review
  6. Article
  7. Evolution and Potential Subfunctionalization of DuplicatedJournal of immunology (Baltimore, Md. : 1950) · 2022
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Mrinal Samanta *Fish Health Management Division, ICAR-Central Institute of Freshwater Aquaculture (CIFA), Kausalyaganga, Bhubaneswar, Odisha, India.
Jinyeong Yim *Department of Microbiology and Immunology, University of Rochester, Rochester, New York, USA.
Francisco De Jesús Andino *Department of Microbiology and Immunology, University of Rochester, Rochester, New York, USA.
Matthieu PaiolaDepartment of Microbiology and Immunology, University of Rochester, Rochester, New York, USA.
Jacques RobertDepartment of Microbiology and Immunology, University of Rochester, Rochester, New York, USA Jacques_Robert@urmc.rochester.edu.ORCID 0000-0003-4380-1476
University of Rochester · USCentral Institute of Freshwater Aquaculture · IN

Funding

A Xenopus Laevis Research Resource for ImmunologyR24AI059830 · NIAID · UNIVERSITY OF ROCHESTER · PI JACQUES Robert · 2004 to 2026
$7.7M
NIAID NIH HHS R24 AI059830
6 · The paper itself

Abstract

Ranaviruses such as frog virus 3 (FV3) are large double-stranded DNA (dsDNA) viruses causing emerging infectious diseases leading to extensive morbidity and mortality of amphibians and other ectothermic vertebrates worldwide. Among the hosts of FV3, some are highly susceptible, whereas others are resistant and asymptomatic carriers that can take part in disseminating the infectious virus. To date, the mechanisms involved in the processes of FV3 viral persistence associated with subclinical infection transitioning to lethal outbreaks remain unknown. Investigation in

Indexed as

Virus ActivationAnimalsCarrier StateCytokinesDNA Virus InfectionsEscherichia coliFlagellinGene ExpressionInflammationMacrophages, PeritonealNLR ProteinsRanavirusSignal TransductionToll-Like Receptor 5Toll-Like ReceptorsViral LoadCytokinesFlagellinNLR ProteinsToll-Like Receptor 5Toll-Like ReceptorsXenopus Proteinsamphibian declineinfectious diseasesinnate receptorsranavirusTLRviral persistence

Identifiers

PMID33827949
PMCPMC8316112
OpenAlexW3144087952

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.