Evidence map›Paper›PMID 33827856›Full record

ArticleBMJ open respiratory research2021

Symptomatic, biochemical and radiographic recovery in patients with COVID-19.

Patrick Mallia, Jamilah Meghji, Brandon Wong, Kartik Kumar, Victoria Pilkington, Shaan Chhabra, Ben Russell, Jian Chen, Karthikan Srikanthan, Mirae Park and 24 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open respiratory research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Understanding how social determinants of health shape Long COVID outcomes: a rapid review of evidence.Archives of public health = Archives belges de sante publique · 2025
    Pooled it
  2. Prevalence, risk factors and treatments for post-COVID-19 breathlessness: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2022
    Pooled it
  3. ESCMID rapid guidelines for assessment and management of long COVID.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2022
    Guideline
  4. Trial
  5. Observational
  6. Article
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors at 2 institutions in 1 country.

Patrick Mallia *Imperial College Healthcare NHS Trust, London, UK p.mallia@imperial.ac.uk.ORCID 0000-0002-5747-9978
Jamilah MeghjiImperial College Healthcare NHS Trust, London, UK.
Brandon WongImperial College Healthcare NHS Trust, London, UK.
Kartik KumarImperial College Healthcare NHS Trust, London, UK.
Victoria PilkingtonImperial College Healthcare NHS Trust, London, UK.
Shaan ChhabraImperial College Healthcare NHS Trust, London, UK.
Ben RussellImperial College Healthcare NHS Trust, London, UK.
Jian ChenImperial College Healthcare NHS Trust, London, UK.
Karthikan SrikanthanImperial College Healthcare NHS Trust, London, UK.
Mirae ParkImperial College Healthcare NHS Trust, London, UK.
Harriet OwlesImperial College Healthcare NHS Trust, London, UK.
Felicity LiewImperial College Healthcare NHS Trust, London, UK.
Joana AlcadaImperial College Healthcare NHS Trust, London, UK.
Laura MartinImperial College Healthcare NHS Trust, London, UK.
Meg ColemanImperial College Healthcare NHS Trust, London, UK.
Sarah ElkinImperial College Healthcare NHS Trust, London, UK.
Clare RossImperial College Healthcare NHS Trust, London, UK.
Shweta AgrawalImperial College Healthcare NHS Trust, London, UK.
Thomas GardinerImperial College Healthcare NHS Trust, London, UK.
Aaron BellImperial College Healthcare NHS Trust, London, UK.
Alice WhiteImperial College Healthcare NHS Trust, London, UK.
Dominic HampsonImperial College Healthcare NHS Trust, London, UK.
Gauri VithlaniImperial College Healthcare NHS Trust, London, UK.
Kavina ManalanImperial College Healthcare NHS Trust, London, UK.
Solange BramerImperial College School of Medicine, Imperial College, London, UK.
Alejandra Martin SeguraImperial College School of Medicine, Imperial College, London, UK.
Anushree KucheriaImperial College School of Medicine, Imperial College, London, UK.
Prashanthi RatnakumarImperial College Healthcare NHS Trust, London, UK.
Alexander SheekaImperial College Healthcare NHS Trust, London, UK.
Lavanya AnandanImperial College Healthcare NHS Trust, London, UK.
Susan CopleyRadiology Department, Imperial College Healthcare NHS Trust, London, UK.
Georgina RussellImperial College Healthcare NHS Trust, London, UK.
Chloe I BloomNational Heart and Lung Institute, Imperial College, London, UK.
Onn Min Kon *Imperial College Healthcare NHS Trust, London, UK.ORCID 0000-0003-2647-4688
Imperial College Healthcare NHS Trust · GBImperial College London · GB

Funding

Medical Research Council MR/S02042X/1
6 · The paper itself

Abstract

backgroundThe symptoms, radiography, biochemistry and healthcare utilisation of patients with COVID-19 following discharge from hospital have not been well described.

methodsRetrospective analysis of 401 adult patients attending a clinic following an index hospital admission or emergency department attendance with COVID-19. Regression models were used to assess the association between characteristics and persistent abnormal chest radiographs or breathlessness.

results75.1% of patients were symptomatic at a median of 53 days post discharge and 72 days after symptom onset and chest radiographs were abnormal in 47.4%. Symptoms and radiographic abnormalities were similar in PCR-positive and PCR-negative patients. Severity of COVID-19 was significantly associated with persistent radiographic abnormalities and breathlessness. 18.5% of patients had unscheduled healthcare visits in the 30 days post discharge.

conclusionsPatients with COVID-19 experience persistent symptoms and abnormal blood biomarkers with a gradual resolution of radiological abnormalities over time. These findings can inform patients and clinicians about expected recovery times and plan services for follow-up of patients with COVID-19.

Indexed as

AftercareCOVID-19Radiography, ThoracicSymptom AssessmentBiomarkersFemaleHumansMaleMiddle AgedPatient Acceptance of Health CarePatient DischargeRecovery of FunctionRetrospective StudiesSARS-CoV-2Severity of Illness IndexTime FactorsBiomarkersCOVID-19

Identifiers

PMID33827856
PMCPMC8029037
OpenAlexW3141850355

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.