ArticleBMJ open2021
Trends in long-term opioid prescriptions for musculoskeletal conditions in Australian general practice: a national longitudinal study using MedicineInsight, 2012-2018.
Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 27 citations in OpenAlex.
- Trial
- The impact of opioid prescribing guidelines on opioid dispensation: A systematic review and meta-analysis.Canadian journal of pain = Revue canadienne de la douleur · 2026Review
- Implementation of an Australian helpline for low back pain: protocol of a type 2 hybrid effectiveness-implementation trial.BMJ open · 2025Article
- Article
- Longitudinal patterns of opioid dispensing dosages for compensated Australian workers with low back pain: a 3.5-year follow-up study.Pain medicine (Malden, Mass.) · 2025Article
- Concurrent Prescribing of Opioids and Sedative-Hypnotic Drugs for Long-Term Use in Australian General Practice: A Cross-Sectional Analysis Using MedicineInsight.Pharmacology research & perspectives · 2025Article
- Is low-value care for persistent musculoskeletal pain more common in rural than urban areas? A scoping review.BMC health services research · 2025Article
- 'Overhaul Medicare and perhaps train us better': a qualitative study of primary care general practitioners' perspectives on how to implement the low back pain clinical care standards.BMJ public health · 2025Article
- Minimising Harm and Managing Pain: Deprescribing Opioids in Older Adults.Drugs & aging · 2024Review
- A digital health intervention to support patients with chronic pain during prescription opioid tapering: a pilot randomised controlled trial.Pain reports · 2024Article
- Article
- Prevalence and characteristics of musculoskeletal complaints in primary care: an analysis from the population level and analysis reporting (POLAR) database.BMC primary care · 2023Article
- Opioids and Falls Risk in Older Adults: A Narrative Review.Drugs & aging · 2022Review
- A pharmacist-led intervention to improve the management of opioids in a general practice: a qualitative evaluation of participant interviews.International journal of clinical pharmacy · 2022Article
- Long-term benzodiazepines and z-drug prescribing in Australian general practice between 2011 and 2018: A national study.Pharmacology research & perspectives · 2022Article
- Evaluating the accuracy of data extracted from electronic health records into MedicineInsight, a national Australian general practice database.International journal of population data science · 2022Article
- Using electronic admission data to monitor temporal trends in local medication use: Experience from an Australian tertiary teaching hospital.Frontiers in pharmacology · 2022Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveDescribe trends and patterns in long-term opioid prescriptions among adults with musculoskeletal conditions (MSK).
designInterrupted time-series analysis based on an open cohort study.
settingA representative sample of 402 Australian general practices contributing data to the MedicineInsight database.
participants811 174 patients aged 18+ years with an MSK diagnosis and three or more consultations in any two consecutive years between 2012 and 2018. Males represented 44.5% of the sample, 28.4% were 65+ years and 1.9% were Aboriginal or Torres Strait Islanders. PRIMARY AND SECONDARY OUTCOME MEASURES: Annual prevalence and cumulative incidence (%) of long-term opioid prescribing (3+ prescriptions in 90 days) among patients with an MSK. Average duration of these episodes in each year between 2012 and 2018.
resultsThe prevalence of long-term opioid prescribing increased from 5.5% (95% CI 5.2 to 5.8) in 2012 to 9.1% (95% CI 8.8 to 9.7) in 2018 (annual change OR 1.09, 95% CI 1.08 to 1.09), but a slightly lower incidence was observed in 2018 (3.0% vs 3.6%-3.8% in other years; annual change OR 0.99, 95% CI 0.98 to 0.99). The incidence was between 37% and 52% higher among practices located in rural Australia or lower socioeconomic areas. Individual risk factors included increasing age (3.4 times higher among those aged 80+ years than the 18-34 years group in 2012, increasing to 4.8 times higher in 2018), identifying as Aboriginal or Torres Strait Islander (1.7-1.9 higher incidence than their peers), or living in disadvantaged areas (36%-57% more likely than among those living in wealthiest areas). Long-term opioid prescriptions lasted in average 287-301 days between 2012 and 2016, reducing to 229 days in 2017 and 140 days in 2018. A longer duration was observed in practices from more disadvantaged areas and females in all years, except in 2018.
conclusionsThe continued rise in the prevalence of long-term opioid prescribing is of concern, despite a recent reduction in the incidence and duration of opioid management.
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