ArticleScience advances2021
Discovery of a natural cyan blue: A unique food-sourced anthocyanin could replace synthetic brilliant blue.
Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 61 citations in OpenAlex.
- Design of a sustained-release nanosystem for ultra-efficient absorption of anthocyanins and regulating lung damage through the "lung-gut" axis.Journal of advanced research · 2026Article
- Comprehensive engineering of novel glycosyltransferase for efficient, donor-promiscuous, and regioselective glycosylation of flavonoids.Science advances · 2025Article
- Humans perceive but animals don't: pitfalls in using plasticine models for assessing biotic interactions.Proceedings. Biological sciences · 2025Article
- Design and Analysis of Untargeted Metabolomics Experiments.Current protocols · 2025Article
- Metal-free production of natural blue colorants through anthocyanin-protein interactions.Journal of advanced research · 2025Article
- Self-assembled, disordered structural color from fruit wax bloom.Science advances · 2024Article
- Expression and Purification of Cp3GT: Structural Analysis and Modeling of a Key Plant Flavonol-3-O Glucosyltransferase fromBiotech (Basel (Switzerland)) · 2024Article
- Environmental Stimuli and Phytohormones in Anthocyanin Biosynthesis: A Comprehensive Review.International journal of molecular sciences · 2023Review
- Protein and Peptide-Based Nanotechnology for Enhancing Stability, Bioactivity, and Delivery of Anthocyanins.Advanced healthcare materials · 2023Review
- A theory for colors of strongly correlated electronic systems.Nature communications · 2023Article
- Conjugated cross-linked phosphine as broadband light or sunlight-driven photocatalyst for large-scale atom transfer radical polymerization.Nature communications · 2023Article
- Pharmacology of pannexin channels.Current opinion in pharmacology · 2023Review
- Self-Powered Edible Defrosting Sensor.ACS sensors · 2022Article
- Improved Stability of Blue Colour of Anthocyanins fromMolecules (Basel, Switzerland) · 2022Article
- Foodomics: A Data-Driven Approach to Revolutionize Nutrition and Sustainable Diets.Frontiers in nutrition · 2022Article
- Anthocyanins fromMolecules (Basel, Switzerland) · 2021Article
- Acylated Anthocyanins from Red Cabbage and Purple Sweet Potato Can Bind Metal Ions and Produce Stable Blue Colors.International journal of molecular sciences · 2021Article
Corrections and comments
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Authors and funding
22 authors at 10 institutions in 6 countries.
Funding
Abstract
The color of food is critical to the food and beverage industries, as it influences many properties beyond eye-pleasing visuals including flavor, safety, and nutritional value. Blue is one of the rarest colors in nature's food palette-especially a cyan blue-giving scientists few sources for natural blue food colorants. Finding a natural cyan blue dye equivalent to FD&C Blue No. 1 remains an industry-wide challenge and the subject of several research programs worldwide. Computational simulations and large-array spectroscopic techniques were used to determine the 3D chemical structure, color expression, and stability of this previously uncharacterized cyan blue anthocyanin-based colorant. Synthetic biology and computational protein design tools were leveraged to develop an enzymatic transformation of red cabbage anthocyanins into the desired anthocyanin. More broadly, this research demonstrates the power of a multidisciplinary strategy to solve a long-standing challenge in the food industry.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.