ReviewDeutsches Arzteblatt international2021
Idiopathic Facial Pain Syndromes–An Overview and Clinical Implications.
Review in Deutsches Arzteblatt international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 25 citations in OpenAlex.
- Trigeminal nociceptive somatotopy across brainstem and cortex and their functional interactions.The journal of headache and pain · 2026Article
- Internal Jugular Vein Entrapment: An Underrecognized Cause of Facial Pain.European journal of neurology · 2026Article
- Response to the letter regarding "Diagnosis and management of persistent idiopathic facial pain following dental procedures: a retrospective study".Journal of the Korean Association of Oral and Maxillofacial Surgeons · 2026Article
- Rare Primary Headaches in Children: A Narrative Review.Biomedicines · 2026Review
- Internal neurolysis for atypical facial pain: Clinical outcomes and validation of an intraoperative trigeminal pathology scoring system.Surgical neurology international · 2026Article
- Diagnosis and management of persistent idiopathic facial pain following dental procedures: a retrospective study.Journal of the Korean Association of Oral and Maxillofacial Surgeons · 2025Article
- Working-age patients with medically unexplained oral symptoms who receive public assistance in Japan.Scientific reports · 2025Article
- Sphenoid sinus hyperpneumatization: anatomical variants, molecular blueprints, and AI-augmented roadmaps for skull base surgery.Frontiers in endocrinology · 2025Review
- Misdiagnosis-Driven Dental Extractions in Patients with Trigeminal Neuralgia: A Retrospective Study.Journal of multidisciplinary healthcare · 2025Article
- Orofacial migraine and neurovascular orofacial pain-new insights into characteristics and classification.Journal of oral & facial pain and headache · 2024Article
- Severe facial pain and removal of maxillary sinus mucous retention cyst.BMJ case reports · 2024Article
- Radiofrequency thermocoagulation under neuromonitoring guidance and general anesthesia for treatment of refractory trigeminal neuralgia.Acta neurochirurgica · 2024Article
- Advancements in Understanding and Classifying Chronic Orofacial Pain: Key Insights from Biopsychosocial Models and International Classifications (ICHD-3, ICD-11, ICOP).Biomedicines · 2023Review
- Orofacial Migraine and Other Idiopathic Non-Dental Facial Pain Syndromes: A Clinical Survey of a Social Orofacial Patient Group.International journal of environmental research and public health · 2023Article
- Orofacial Pain and Dentistry Management: Guidelines for a More Comprehensive Evidence-Based Approach.Diagnostics (Basel, Switzerland) · 2023Review
- A Case Report of Sphenopalatine Ganglion Block Relieving Chronic Pain Post-Dental Bone Graft Surgery.Cureus · 2023Article
- Improvement in persistent idiopathic facial pain with comorbid ADHD using the combination of a dopamine system stabilizer and psychostimulant: A case report.Clinical case reports · 2023Article
- Idiopathic Non-Dental Facial Pain Syndromes in Italian Children: A Clinical Case Series.Life (Basel, Switzerland) · 2023Article
- Diagnosis and treatment of intractable idiopathic orofacial pain with attention-deficit/hyperactivity disorder.Scientific reports · 2023Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIdiopathic facial pain syndromes are relatively rare. A uniform classification system for facial pain became available only recently, and many physicians and dentists are still unfamiliar with these conditions. As a result, patients frequently do not receive appropriate treatment.
methodsThis article is based on pertinent publications retrieved by a selective search in PubMed, focusing on current international guidelines and the International Classification of Orofacial Pain (ICOP).
resultsThe ICOP subdivides orofacial pain syndromes into six major groups, the first three of which consist of diseases of the teeth, the periodontium, and the temporomandibular joint. The remaining three groups (non-dental facial pain) are discussed in the present review. Attack-like facial pain syndromes most closely resemble the well-known primary headache syndromes, such as migraine, but with pain located below the orbitomeatal line. These syndromes are treated in accordance with the guidelines for the corresponding types of headache. Persistent idiopathic facial pain (PIFP) is a chronic pain disorder with persistent, undulating pain in the face and/or teeth, without any structural correlate. Since this type of pain tends to become chronified after invasive procedures, no dental procedures should be performed to treat it if the teeth are healthy; rather, the treatmentis similar to that of neuropathic pain, e.g., with antidepressant and anticonvulsive drugs. Neuropathic facial pain is also undulating and persistent. It is often described as a burning sensation, and neuralgiform attacks may additionally be present. Trigeminal neuralgia is a distinct condition involving short-lasting, lancinating pain of high intensity with a maximum duration of two minutes. The first line of treatment is with medications; invasive treatment options should be considered only if pharmacotherapy is ineffective or poorly tolerated.
conclusionWith the aid of this pragmatic classification system, the clinician can distinguish persistent and attack-like primary facial pain syndromes rather easily and treat each syndrome appropriately.
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