Evidence map›Paper›PMID 33827703›Full record

ArticleBMC pharmacology & toxicology2021

Coenzyme Q

Victoria K Mwaeni, James N Nyariki, Ngalla Jillani, George Omwenga, Mathew Ngugi, Alfred Orina Isaac

Open access · goldAbstract read
In one paragraph

Article in BMC pharmacology & toxicology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Coenzyme Q10 and Xenobiotic Metabolism: An Overview.International journal of molecular sciences · 2025
    Review
  3. Article
  4. Chia seeds and coenzyme QScientific reports · 2023
    Article
  5. Review
  6. Coenzyme QJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2023
    Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Victoria K MwaeniDepartment of Biochemistry and Biotechnology, Technical University of Kenya, P. O. Box 52428, Nairobi, 00200, Kenya.
James N NyarikiDepartment of Biochemistry and Biotechnology, Technical University of Kenya, P. O. Box 52428, Nairobi, 00200, Kenya.
Ngalla JillaniInstitute of Primate Research, P.O. Box 24481, Karen, Nairobi, 00502, Kenya.
George OmwengaDepartment of Biochemistry, Microbiology and Biotechnology, Kenyatta University, P.O. Box 43844-00100, Nairobi, Kenya.
Mathew NgugiDepartment of Biochemistry, Microbiology and Biotechnology, Kenyatta University, P.O. Box 43844-00100, Nairobi, Kenya.
Alfred Orina IsaacDepartment of Pharmaceutical Sciences and Technology, Technical University of Kenya, P. O. Box 52428, Nairobi, 00200, Kenya. alfred.orina@tukenya.ac.ke.
Technical University of Kenya · KEKenyatta University · KEInstitute of Primate Research · KE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArsenic poisoning affects millions of people. The inorganic forms of arsenic are more toxic. Treatment for arsenic poisoning relies on chelation of extracellularly circulating arsenic molecules by 2,3-dimecaptosuccinic acid (DMSA). As a pharmacological intervention, DMSA is unable to chelate arsenic molecules from intracellular spaces. The consequence is continued toxicity and cell damage in the presence of DMSA. A two-pronged approach that removes extracellular arsenic, while protecting from the intracellular arsenic would provide a better pharmacotherapeutic outcome. In this study, Coenzyme Q

methodsGroup one represented the control; the second group was treated with NaAsO

resultsAdministration of CoQ

conclusionsFindings from this study demonstrate that CoQ

Indexed as

AnimalsAntidotesArsenic PoisoningArsenitesBlood CellsBrainChelating AgentsDrug Therapy, CombinationGlutathioneHematocritKidneyLiverMaleMiceProtective AgentsSodium CompoundsAntidotesArsenitesChelating Agentscoenzyme Q10GlutathioneProtective Agentssodium arseniteSodium CompoundsSuccimerUbiquinoneGlutathioneImmune responseInflammationOrgan metal damageUbiquinone

Identifiers

PMID33827703
PMCPMC8028750
OpenAlexW3146296968

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.