ArticleGenome biology2021
Response to correspondence on "Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation".
Open access · goldAbstract readLetterComment
In one paragraph
Article in Genome biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 12 citations in OpenAlex.
- CoordinatedeLife · 2025Article
- Muc4 loss mitigates epidermal growth factor receptor activity essential for PDAC tumorigenesis.Oncogene · 2023Article
- Introduction of loxP sites by electroporation in the mouse genome; a simple approach for conditional allele generation in complex targeting loci.BMC biotechnology · 2022Article
Corrections and comments
- Comment on
- Comment on
- Comment on
Authors and funding
113 authors at 20 institutions in 7 countries.
Channabasavaiah B GurumurthyMouse Genome Engineering Core Facility, Vice Chancellor for Research Office, University of Nebraska Medical Center, Omaha, NE, USA. cgurumurthy@unmc.edu.
Aidan R O'BrienTransformational Bioinformatics, Health and Biosecurity Business Unit, CSIRO, Sydney, Australia.
Rolen M QuadrosMouse Genome Engineering Core Facility, Vice Chancellor for Research Office, University of Nebraska Medical Center, Omaha, NE, USA.
John AdamsTexas A&M Institute for Genomic Medicine (TIGM), Texas A&M University, College Station, TX, 77843, USA.
Pilar AlcaideDepartment of Immunology, Tufts University School of Medicine, Boston, USA.
Shinya AyabeRIKEN BioResource Research Center, Tsukuba, Ibaraki, 305-0074, Japan.
Johnathan BallardTexas A&M Institute for Genomic Medicine (TIGM), Texas A&M University, College Station, TX, 77843, USA.
Surinder K BatraDepartment of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA.
Marie-Claude BeauchampDepartments of Anatomy and Cell Biology, Human Genetics and Pediatrics, Research Institute McGill University Health Center (RI-MUHC), Montreal, Canada.
Kathleen A BeckerMaine Medical Center Research Institute (MMCRI), Scarborough, ME, USA.
Guillaume BernasTransgenesis and Animal Modeling Core Facility, Centre de Recherche du Centre Hospitalier Universitaire de Montreal (CRCHUM), Montreal, Canada.
David BroughDivision of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, AV Hill Building, Oxford Road, Manchester, M13 9PT, UK.
Francisco Carrillo-SalinasDepartment of Immunology, Tufts University School of Medicine, Boston, USA.
Wesley ChanDepartments of Anatomy and Cell Biology, Human Genetics and Pediatrics, Research Institute McGill University Health Center (RI-MUHC), Montreal, Canada.
Hanying ChenSchool of Medicine, Indiana University, Indianapolis, IN, 46202, USA.
Ruby DawsonSouth Australian Health & Medical Research Institute and Department of Medicine, University of Adelaide, Adelaide, Australia.
Victoria DeMambroMaine Medical Center Research Institute (MMCRI), Scarborough, ME, USA.
Jinke D'HontTransgenic mouse core facility, VIB Center for Inflammation Research, Ghent, Belgium.
Katharine DibbUnit of Cardiac Physiology, School of Medical Sciences, Manchester Academic Health Science Center, University of Manchester, Manchester, UK.
James D EudyHigh-Throughput DNA Sequencing and Genotyping Core Facility, Vice Chancellor for Research Office, University of Nebraska Medical Center, Omaha, USA.
Lin GanUniversity of Rochester Medical Center, Rochester, NY, 14642, USA.
Jing GaoDepartment of Immunology and Infectious Disease, the John Curtin School of Medical Research, The Australian National University, Canberra, Australia.
Amy GonzalesTexas A&M Institute for Genomic Medicine (TIGM), Texas A&M University, College Station, TX, 77843, USA.
Anyonya GunturMaine Medical Center Research Institute (MMCRI), Scarborough, ME, USA.
Huiping GuoTexas A&M Institute for Genomic Medicine (TIGM), Texas A&M University, College Station, TX, 77843, USA.
Donald W HarmsMouse Genome Engineering Core Facility, Vice Chancellor for Research Office, University of Nebraska Medical Center, Omaha, NE, USA.
Anne HarringtonMaine Medical Center Research Institute (MMCRI), Scarborough, ME, USA.
Kathryn E HentgesDivision of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.
Neil HumphreysTransgenic Unit core facility, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Shiho ImaiDepartment of Basic Medicine, Division of Basic Medical Science and Molecular Medicine, School of Medicine, Tokai University, 143, Shimokasuya, Isehara, Kanagawa, 259-1193, Japan.
Hideshi IshiiDepartment of Medical Data Science, Osaka University Graduate School of Medicine, Suita, Japan.
Mizuho IwamaRIKEN BioResource Research Center, Tsukuba, Ibaraki, 305-0074, Japan.
Eric JonaschThe University of Texas, MD Anderson Cancer Center, Houston, TX, USA.
Michelle KarolakMaine Medical Center Research Institute (MMCRI), Scarborough, ME, USA.
Bernard KeavneyDivision of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester AND Manchester Heart Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.
Nay-Chi KhinDepartment of Immunology and Infectious Disease, the John Curtin School of Medical Research, The Australian National University, Canberra, Australia.
Masamitsu KonnoDepartment of Frontier Science for Cancer and Chemotherapy, Osaka University Graduate School of Medicine, Osaka, Japan.
Yuko KotaniThe Institute of Experimental Animal Sciences, Osaka University Graduate School of Medicine, Osaka, Japan.
Yayoi KunihiroThe Institute of Experimental Animal Sciences, Osaka University Graduate School of Medicine, Osaka, Japan.
Imayavaramban LakshmananDepartment of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA.
Catherine LarochelleCentre de Recherche du Centre Hospitalier Universitaire de Montreal (CRCHUM), Montreal, Canada.
Catherine B LawrenceDivision of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, AV Hill Building, Oxford Road, Manchester, M13 9PT, UK.
Lin LiChildren's Research Institute Mouse Genome Engineering Core, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
Volkhard LindnerMaine Medical Center Research Institute (MMCRI), Scarborough, ME, USA.
Xian-De LiuThe University of Texas, MD Anderson Cancer Center, Houston, TX, USA.
Gloria Lopez-CastejonManchester Collaborative Centre for Inflammation Research (MCCIR), School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.
Andrew LoudonCentre for Biological Timing, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Jenna LoweDepartment of Immunology and Infectious Disease, the John Curtin School of Medical Research, The Australian National University, Canberra, Australia.
Loydie Jerome-MajeweskaDepartments of Anatomy and Cell Biology, Human Genetics and Pediatrics, Research Institute McGill University Health Center (RI-MUHC), Montreal, Canada.
Taiji MatsusakaDepartment of Basic Medicine, Division of Basic Medical Science and Molecular Medicine, School of Medicine, Tokai University, 143, Shimokasuya, Isehara, Kanagawa, 259-1193, Japan.
Hiromi MiuraCenter for Matrix Biology and Medicine, Graduate School of Medicine, Tokai University, Isehara, Kanagawa, 259-1193, Japan.
Yoshiki MiyasakaThe Institute of Experimental Animal Sciences, Osaka University Graduate School of Medicine, Osaka, Japan.
Benjamin MorpurgoTexas A&M Institute for Genomic Medicine (TIGM), Texas A&M University, College Station, TX, 77843, USA.
Katherine MotylMaine Medical Center Research Institute (MMCRI), Scarborough, ME, USA.
Yo-Ichi NabeshimaLaboratory of Molecular Life Science, Foundation for Biomedical Research and Innovation, Kobe, Japan.
Koji NakadeRIKEN BioResource Research Center, Tsukuba, Ibaraki, 305-0074, Japan.
Toshiaki NakashibaRIKEN BioResource Research Center, Tsukuba, Ibaraki, 305-0074, Japan.
Kenichi NakashimaRIKEN BioResource Research Center, Tsukuba, Ibaraki, 305-0074, Japan.
Yuichi ObataRIKEN BioResource Research Center, Tsukuba, Ibaraki, 305-0074, Japan.
Sanae OgiwaraDepartment of Laboratory Animal Science, Support Center for Medical Research and Education, Tokai University, 143, Shimokasuya, Isehara, Kanagawa, 259-1193, Japan.
Mariette OuelletTransgenesis and Animal Modeling Core Facility, Centre de Recherche du Centre Hospitalier Universitaire de Montreal (CRCHUM), Montreal, Canada.
Leif OxburghMaine Medical Center Research Institute (MMCRI), Scarborough, ME, USA.
Sandra PiltzSouth Australian Health & Medical Research Institute and Department of Medicine, University of Adelaide, Adelaide, Australia.
Ilka PinzMaine Medical Center Research Institute (MMCRI), Scarborough, ME, USA.
Moorthy P PonnusamyDepartment of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA.
David RayOxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, OX37LE, UK.
Ronald J RedderHigh-Throughput DNA Sequencing and Genotyping Core Facility, Vice Chancellor for Research Office, University of Nebraska Medical Center, Omaha, USA.
Clifford J RosenMaine Medical Center Research Institute (MMCRI), Scarborough, ME, USA.
Nikki RossDepartment of Immunology and Infectious Disease, the John Curtin School of Medical Research, The Australian National University, Canberra, Australia.
Mark T RuheMouse Biology Program, University of California, Davis, USA.
Larisa RyzhovaMaine Medical Center Research Institute (MMCRI), Scarborough, ME, USA.
Ane M SalvadorDepartment of Immunology, Tufts University School of Medicine, Boston, USA.
Sabrina Shameen AlamDepartments of Anatomy and Cell Biology, Human Genetics and Pediatrics, Research Institute McGill University Health Center (RI-MUHC), Montreal, Canada.
Radislav SedlacekLaboratory of Transgenic Models of Diseases and Czech Centre for Phenogenomics, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic.
Karan SharmaCollege of Osteopathic Medicine, Marian University, Indianapolis, IN, 46222, USA.
Chad SmithThe University of Texas, MD Anderson Cancer Center, Houston, TX, USA.
Katrien StaesTransgenic mouse core facility, VIB Center for Inflammation Research, Ghent, Belgium.
Lora StarrsDepartment of Immunology and Infectious Disease, the John Curtin School of Medical Research, The Australian National University, Canberra, Australia.
Fumihiro SugiyamaLaboratory Animal Resource Center, University of Tsukuba, Tsukuba, Japan.
Satoru TakahashiLaboratory Animal Resource Center, University of Tsukuba, Tsukuba, Japan.
Tomohiro TanakaDepartment of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
Andrew TraffordUnit of Cardiac Physiology, School of Medical Sciences, Manchester Academic Health Science Center, University of Manchester, Manchester, UK.
Yoshihiro UnoThe Institute of Experimental Animal Sciences, Osaka University Graduate School of Medicine, Osaka, Japan.
Leen VanhoutteTransgenic mouse core facility, VIB Center for Inflammation Research, Ghent, Belgium.
Frederique VanrockeghemTransgenic mouse core facility, VIB Center for Inflammation Research, Ghent, Belgium.
Brandon J WillisMouse Biology Program, University of California, Davis, USA.
Christian S WrightDepartment of Physical Therapy, School of Health and Human Sciences, Indiana University, Indianapolis, IN, 46202, USA.
Yuko YamauchiThe Institute of Experimental Animal Sciences, Osaka University Graduate School of Medicine, Osaka, Japan.
Xin YiDepartment of Physical Therapy, School of Health and Human Sciences, Indiana University, Indianapolis, IN, 46202, USA.
Kazuto YoshimiThe Institute of Experimental Animal Sciences, Osaka University Graduate School of Medicine, Osaka, Japan.
Xuesong ZhangThe University of Texas, MD Anderson Cancer Center, Houston, TX, USA.
Yu ZhangChildren's Research Institute Mouse Genome Engineering Core, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
Masato OhtsukaCenter for Matrix Biology and Medicine, Graduate School of Medicine, Tokai University, Isehara, Kanagawa, 259-1193, Japan.
Satyabrata DasLillehei Heart Institute Regenerative Medicine and Sciences Program, University of Minnesota, Minneapolis, MN, USA.
Daniel J GarryLillehei Heart Institute Regenerative Medicine and Sciences Program, University of Minnesota, Minneapolis, MN, USA.
Tino HochepiedTransgenic mouse core facility, VIB Center for Inflammation Research, Ghent, Belgium.
Paul ThomasSouth Australian Health & Medical Research Institute and Department of Medicine, University of Adelaide, Adelaide, Australia.
Jan Parker-ThornburgThe University of Texas, MD Anderson Cancer Center, Houston, TX, USA.
Antony D AdamsonTransgenic Unit core facility, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Atsushi YoshikiRIKEN BioResource Research Center, Tsukuba, Ibaraki, 305-0074, Japan.
Jean-Francois SchmouthTransgenesis and Animal Modeling Core Facility, Centre de Recherche du Centre Hospitalier Universitaire de Montreal (CRCHUM), Montreal, Canada.
Andrei GolovkoTexas A&M Institute for Genomic Medicine (TIGM), Texas A&M University, College Station, TX, 77843, USA.
William R ThompsonDepartment of Physical Therapy, School of Health and Human Sciences, Indiana University, Indianapolis, IN, 46202, USA.
K C Kent LloydMouse Biology Program, University of California, Davis, USA.
Joshua A WoodMouse Biology Program, University of California, Davis, USA.
Mitra CowanMcGill Integrated Core for Animal Modeling (MICAM), Montreal, Canada.
Tomoji MashimoThe Institute of Experimental Animal Sciences, Osaka University Graduate School of Medicine, Osaka, Japan.
Seiya MizunoLaboratory Animal Resource Center, University of Tsukuba, Tsukuba, Japan.
Hao ZhuChildren's Research Institute Mouse Genome Engineering Core, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
Petr KasparekLaboratory of Transgenic Models of Diseases and Czech Centre for Phenogenomics, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic.
Lucy LiawMaine Medical Center Research Institute (MMCRI), Scarborough, ME, USA.
Joseph M MianoUniversity of Rochester Medical Center, Rochester, NY, 14642, USA.
Gaetan BurgioDepartment of Immunology and Infectious Disease, the John Curtin School of Medical Research, The Australian National University, Canberra, Australia. gaetan.burgio@anu.edu.au.
Maine Medical Center Research Institute · USOsaka University · JPUniversity of Manchester · GBAustralian National University · AURIKEN BioResource Research Center · JPUniversity of Nebraska Medical Center · USTexas A&M University · USThe University of Texas MD Anderson Cancer Center · USTokai University · JPCentre Hospitalier de l’Université de Montréal · CAMcGill University Health Centre · CAUniversity of California, Davis · USGhent University · BEIndiana University IndianapolisThe University of Texas Southwestern Medical Center · USTufts University · USUniversity of Tsukuba · JPCzech Academy of Sciences, Institute of Molecular Genetics · CZMinneapolis Heart Institute Foundation · USSouth Australian Health and Medical Research Institute · AU
Funding
British Heart Foundation CH/13/2/30154Medical Research Council MR/M008908/1Medical Research Council MR/P023576/2Wellcome Trust 107851/Z/15/Z
Abstract
PubMed holds no abstract for this paper.
Indexed as
CRISPR-Associated Protein 9CRISPR-Cas SystemsAllelesAnimalsGene EditingMiceReproducibility of ResultsCRISPR-Associated Protein 9
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.