Evidence map›Paper›PMID 33827472›Full record

ArticleBMC nephrology2021

Acute interstitial nephritis associated with ingestion of Achyranthes japonica extract: a case report.

Ha Nee Jang, Sehyun Jung, Seunghye Lee, Se-Ho Chang, Tae Won Lee, Eunjin Bae, Dong Jun Park

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC nephrology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ha Nee JangDepartment of Internal Medicine, Gyeongsang National University Hospital, Jinju, South Korea.
Sehyun JungDepartment of Internal Medicine, Gyeongsang National University Hospital, Jinju, South Korea.
Seunghye LeeDepartment of Internal Medicine, Gyeongsang National University Hospital, Jinju, South Korea.
Se-Ho ChangDepartment of Internal Medicine, Gyeongsang National University Hospital, Jinju, South Korea.
Tae Won LeeDepartment of Internal Medicine, Gyeongsang National University Changwon Hospital, 11 Samjungja-ro Sungsan-gu, Changwon, 51472, South Korea.
Eunjin BaeDepartment of Internal Medicine, College of Medicine, Gyeongsang National University, Jinju, South Korea.
Dong Jun ParkDepartment of Internal Medicine, College of Medicine, Gyeongsang National University, Jinju, South Korea. drpdj@naver.com.ORCID 0000-0001-5233-537X
Changwon National University · KRGyeongsang National University Hospital · KRGyeongsang National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Japanese chaff flower, Achyranthes japonica, is used as complementary medicine to control degenerative arthritis. Although commonly used in South Korea, there has been no report of side effects. We report the first case of acute interstitial nephritis (AIN) that occurred in a woman who ingested A. japonica extract for 4 months. CASE PRESENTATION: A 56-year-old Korean woman was admitted for deterioration of renal function. She had general weakness and nausea for 1 month. Her initial blood urea nitrogen and serum creatinine levels were 26.3 mg/dL and 3.2 mg/dL, respectively. She acknowledged ingesting A. japonica extract for the past 4 months. Renal histology demonstrated AIN represented by immune cell infiltration into the interstitium, tubulitis, and tubular atrophy, but the glomeruli were intact. A. japonica was discontinued immediately and conservative management was started. Renal function was nearly restored to the baseline level without medication after 13 months.

conclusionThis is a rare case report of AIN associated with a pure A. japonica extract. In the case of unknown etiology of AIN, physicians should ask about the use of herbal medicines, nutraceuticals, and traditional folk medicines including A. japonica.

Indexed as

AchyranthesCreatinineDietary SupplementsFemaleHerbal MedicineHumansKidneyMiddle AgedNephritis, InterstitialPlant ExtractsCreatininePlant ExtractsAchyranthes japonicaDrugsNephritisNutraceuticalsSide effects

Identifiers

PMID33827472
PMCPMC8028177
OpenAlexW3151245180

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.