Evidence map›Paper›PMID 33827465›Full record

ArticleBMC medical imaging2021

The prognosis prediction significance of Hounsfield unit value for stroke patients treated by intravenous thrombolysis.

Zhengqi Zhu, Ru Zhang, Kaixuan Ren, Ruochen Cong, Xiangyang Zhu, Li Zhu, Tianle Wang

Open access · goldAbstract read
In one paragraph

Article in BMC medical imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Zhengqi ZhuDepartment of Radiology, The Second Affiliated Hospital of Nantong University, 6 Haierxiang North Road, Nantong, 226001, Jiangsu, China.
Ru ZhangDepartment of Radiology, The Second Affiliated Hospital of Nantong University, 6 Haierxiang North Road, Nantong, 226001, Jiangsu, China.
Kaixuan RenDepartment of Radiology, The Second Affiliated Hospital of Nantong University, 6 Haierxiang North Road, Nantong, 226001, Jiangsu, China.
Ruochen CongDepartment of Radiology, The Second Affiliated Hospital of Nantong University, 6 Haierxiang North Road, Nantong, 226001, Jiangsu, China.
Xiangyang ZhuDepartment of Neurology, The Second Affiliated Hospital of Nantong University, Nantong, 226001, China.
Li ZhuDepartment of Radiology, The Second Affiliated Hospital of Nantong University, 6 Haierxiang North Road, Nantong, 226001, Jiangsu, China.
Tianle WangDepartment of Radiology, The Second Affiliated Hospital of Nantong University, 6 Haierxiang North Road, Nantong, 226001, Jiangsu, China. wangtianle9192@163.com.ORCID 0000-0002-7779-1643
Nantong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntravenous thrombolysis (IVT) is a rapid and effective treatment in the early stage of ischemic stroke patients and the purpose of this work is to explore the significance of Hounsfield unit (HU) value in Alberta Stroke Program Early CT Score (ASPECTS) for predicting the clinical prognosis of stroke patients with middle cerebral artery occlusion (MCAO) treated by IVT.

methodsThe 84 stroke patients with MCAO treated by IVT were divided into good prognosis group (48 cases) and poor prognosis group (36 cases). HU ratio and HU difference calculated from non-contrast computed tomography between groups were analyzed.

resultsThe HU ratio of good prognosis group was higher than that in poor prognosis group and the HU difference of good prognosis group was lower than that in poor prognosis group (P < 0.05). The HU ratio and ASPECTS were negatively correlated with the infarct volume, and the HU difference was positively correlated with the infarct volume (P < 0.05). HU difference was an independent risk factor for prognosis of patients with MCAO treated by IVT. The area under the receiver operating characteristic curve of HU ratio and HU difference for prognosis was 0.743 and 0.833 respectively.

conclusionThe HU value changes are related to the clinical prognosis of stroke patients with MCAO treated by IVT, HU value may be a prognostic indicator for stroke patients with MCAO treated by IVT.

Indexed as

AgedCerebral HemorrhageFemaleHumansInfarction, Middle Cerebral ArteryMagnetic Resonance ImagingMalePrognosisRetrospective StudiesRisk FactorsROC CurveThrombolytic TherapyThrombotic StrokeHounsfield unit valueIntravenous thrombolysisPrognosisStroke

Identifiers

PMID33827465
PMCPMC8028233
OpenAlexW3148916450

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.