ArticleBMC infectious diseases2021
Prevalence and genotype distribution of HPV infection among 214,715 women from Southern China, 2012-2018: baseline measures prior to mass HPV vaccination.
Article in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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37 citing papers in PubMed, 51 citations in OpenAlex.
- Safety and immunogenicity of a bivalent HPV16/18 vaccine in Chinese females.Human vaccines & immunotherapeutics · 2023Trial
- HPV DNA Detection and Genotyping in Basal-Like Breast Carcinoma: Insights into a Possible Viral Association.Diagnostics (Basel, Switzerland) · 2026Article
- The Prevalence of Human Papilloma Virus in Turkish Women.Journal of clinical medicine · 2026Article
- Article
- HPV epidemiologic study in Bengbu, China, involving 123,808 women, 2014-2023.Virology journal · 2026Article
- Modelling the epidemic dynamics of HPV among women in China and optimization of ongoing cervical cancer elimination strategies.BMC medicine · 2026Article
- The Relationship Between Body Mass Index and Cervical High-Risk HPV Positivity in Women: A Single-Center Study.Microorganisms · 2026Article
- Factors related to cervicogenital high-risk human papillomavirus persistence among Chinese women: a nationwide multi-center cohort study.Virology journal · 2025Article
- Epidemiological analysis of human papillomavirus infection in senior women: a hospital-based retrospective study.BMC infectious diseases · 2025Article
- Human papillomavirus prevalence and genotype distribution among 30,147 screened women and 3,362 cervical cancer patients in China: a retrospective study.Virology journal · 2025Article
- HPV prevalence and genotype distribution among women in sanming, China: a retrospective analysis before large-scale vaccination.Infectious agents and cancer · 2025Article
- HPV genotype distribution and cervical lesions in Chongqing: a comprehensive analysis of 229,770 females (2015‒2023).BMC infectious diseases · 2025Article
- Age-related distribution of human papillomavirus genotypes in women with cervical squamous cell carcinoma from Linyi, China, 2015-2023.Virology journal · 2025Article
- Characterization of human papillomavirus genotypes infections in patients with cervical lesions and cervical cancer in Urumqi, Xinjiang from 2016 to 2023.Virology journal · 2025Article
- Prevalence and genotype assessment of HPV in 73,697 females from Beijing, China.Frontiers in public health · 2025Article
- Barriers and enablers of HPV vaccination among caregivers of school-age girls in resource-limited regions of Western Sichuan, China: a mixed-methods study.Frontiers in public health · 2025Article
- Epidemiological study of human papillomavirus infection in 105,679 women in Wuhan, China.BMC infectious diseases · 2024Article
- Prevalence and genotype distribution of human papillomavirus infection among 66000 women from 2014 to 2023 in the plateau region of Southwest China.Virology journal · 2024Article
- Characterization of genital chlamydia trachomatis infection among women attending infertility and gynecology clinics in Hunan, China.BMC infectious diseases · 2024Article
- Prevalence and genotype distribution of HPV infections among women in Chengdu,China.Virology journal · 2024Article
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13 authors at 1 institution in 1 country.
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Abstract
backgroundThe epidemiology on the human papillomavirus (HPV) among females in Southern China is not well-established. Baseline data on the prevalence of HPV infection in China prior to mass prophylactic HPV vaccination would be useful. Thus, this study aims to determine the type-specific HPV prevalence and distribution among females from Southern China prior to mass HPV vaccination.
methodsA retrospective cross-sectional study employing 214,715 women attending ChenZhou NO.1 People's Hospital for cervical screening during 2012-2018 was conducted prior to widespread HPV vaccination. HPV genotype was detected using nucleic acid molecular diversion hybridization tests. The overall prevalence, age-specific prevalence, type distribution, and annual trend were analyzed.
resultsThe overall HPV prevalence was 18.71% (95% confidence interval [CI], 18.55-18.88%) among Southern China females. During 2012-2018, the prevalence of HPV infection showed a downward tendency, from 21.63% (95% CI, 21.07-22.20%) in 2012 to 18.75% (95% CI, 18.35-19.16%) in 2018. Age-specific HPV distribution displayed a peak at young women aged less than 21 years (33.11, 95% CI, 31.13-35.15%), 20.07% (95% CI, 19.70-20.44%) among women aged 21-30 years, 17.29% (95% CI, 17.01-17.57%) among women aged 31-40 years, 17.23% (95% CI, 16.95-17.51%) among women aged 41-50 years, 21.65% (95% CI, 21.11-22.20%) among women aged 51-60 years, and 25.95% (95% CI, 24.86-27.07%) among women aged over 60 years. Of the 21 subtypes identified, the top three prevalent high-risk HPV (HR-HPV) genotypes were HPV52 (5.12%; 95% CI, 21.11-22.20%), - 16 (2.96%; 95% CI, 2.89-3.03%), and - 58 (2.51%; 95% CI, 2.44-2.58%); the predominant low-risk HPV (LR-HPV) genotypes were HPV81 (1.86%; 95%CI, 1.80-1.92%) and - 6 (0.69%; 95% CI, 0.66-0.73%) respectively. Incidence of HR-HPV only, LR-HPV only and mixed LR- and HR-HPV were 15.17, 2.07 and 1.47% respectively. Besides, single HPV infection accounted for 77.30% of all positive cases in this study.
conclusionsThis study highlights 1) a high prevalence of HPV infection among females with a decreasing tendency towards 2012-2018, especially for young women under the age of 21 prior to mass HPV vaccination; 2) HPV52, - 16 and - 58 were the predominant HPV genotypes, suggesting potential use of HPV vaccine covering these HPV genotypes in Southern China.
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