Evidence map›Paper›PMID 33827252›Full record

ArticleArteriosclerosis, thrombosis, and vascular biology2021

Gab2 (Grb2-Associated Binder2) Plays a Crucial Role in Inflammatory Signaling and Endothelial Dysfunction.

Vijay Kondreddy, Jhansi Magisetty, Shiva Keshava, L Vijaya Mohan Rao, Usha R Pendurthi

Open access · hybridAbstract read
In one paragraph

Article in Arteriosclerosis, thrombosis, and vascular biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. LPCAT3-dependent remodeling of the phospholipids and lipid rafts is essential for vascular proinflammatory signaling and the development of atherosclerosis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
    Article
  6. Article
  7. Article
  8. Deficiency of Caspase-1 Attenuates HIV-1-Associated Atherogenesis in Mice.International journal of molecular sciences · 2023
    Article
  9. Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Vijay KondreddyDepartment of Cellular and Molecular Biology, The University of Texas Health Science Center at Tyler.
Jhansi MagisettyDepartment of Cellular and Molecular Biology, The University of Texas Health Science Center at Tyler.
Shiva KeshavaDepartment of Cellular and Molecular Biology, The University of Texas Health Science Center at Tyler.
L Vijaya Mohan RaoDepartment of Cellular and Molecular Biology, The University of Texas Health Science Center at Tyler.
Usha R PendurthiDepartment of Cellular and Molecular Biology, The University of Texas Health Science Center at Tyler.
The University of Texas Health Science Center at Tyler · US

Funding

Membrane Phospholipids: The Key Regulators of Tissue Factor Encryption/DecryptionR01HL124055 · NHLBI · UNIVERSITY OF TEXAS HLTH CTR AT TYLER · PI LELLA, VIJAYA MOHAN RAO · 2015 to 2023
$3.3M
Factor VIIa Interaction with Endothelial Cell Protein C ReceptorR01HL107483 · NHLBI · UNIVERSITY OF TEXAS HLTH CTR AT TYLER · PI LELLA, VIJAYA MOHAN RAO · 2012 to 2019
$2.9M
NHLBI NIH HHS R01 HL107483NHLBI NIH HHS R01 HL124055
6 · The paper itself

Abstract

[Figure: see text].

Indexed as

Adaptor Proteins, Signal TransducingAnimalsCytokinesDisease Models, AnimalEndotoxinsExtracellular TrapsFemaleHumansHuman Umbilical Vein Endothelial CellsInflammationInflammation MediatorsLungMaleMiceMice, KnockoutPneumococcal InfectionsAdaptor Proteins, Signal TransducingCytokinesendotoxin, Escherichia coliEndotoxinsGAB2 protein, humanGab2 protein, mouseInflammation MediatorsThrombincell adhesion moleculescytokinesinflammationthromboplastinthrombosis

Identifiers

PMID33827252
PMCPMC8147699
OpenAlexW3140482925

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.