ReviewCell metabolism2021
Insulin action in adipocytes, adipose remodeling, and systemic effects.
Open access · bronzeAbstract readReview
In one paragraph
Review in Cell metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers.
0numbers the graph read from it
0cells of the map it votes in
102citing papers in PubMed
11.9field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
102 citing papers in PubMed, 147 citations in OpenAlex.
- Endocrinological aspects of sarcopenic obesity.Annals of medicine · 2026Review
- Remodelling of body composition surrounding the diagnosis of type 2 diabetes in three longitudinal cohorts.Diabetologia · 2026Article
- Insulin resistance in the 21st century: new takes on an old problem-2025 Diabetes, Diabetes Care, and Diabetologia Expert Forum.Diabetologia · 2026Review
- Functional annotation of insulin-responsive genes in human adipocytes reveals PLCXD1 as a lipid storage regulator.Nature communications · 2026Article
- Chronic low-dose of BPS and PFOS alter adipogenic programming and impair insulin responsiveness in human adipocytes.Journal of endocrinological investigation · 2026Article
- IRF1 in Adipocytes Is Associated with Insulin Signaling and Mitochondrial Homeostasis in Diet-Induced Obesity.International journal of molecular sciences · 2026Article
- Chronic viral infection aggravates white adipose tissue dysfunction and liver pathology in obesity.Molecular metabolism · 2026Article
- SRM-Mediated Spermidine Synthesis Links Lipid Overload With AMPK Pathway to Regulate Hepatic Insulin Signaling and Gluconeogenesis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Article
- Adipose Tissue-Central Nervous System Axis in Obesity: Molecular Mechanisms, Inflammation, and Nutritional and Technological Implications.Metabolites · 2026Review
- GULP1 enhances GLUT4 translocation by counteracting ACAP1-ARF6 inhibition.Nutrition & diabetes · 2026Article
- A primordial synaptotagmin-independent function of complexin in regulated exocytosis.Nature communications · 2026Article
- Adipocyte Pten Inhibition Improves Metabolic Health Associated with Expanded Lipid Storage Capacity and Reduced Inflammation.bioRxiv : the preprint server for biology · 2026Article
- Construction of a Prediction Model for Inadequate Weight Loss After Sleeve Gastrectomy Based on Preoperative Indicators.Obesity surgery · 2026Article
- Beyond Glycemic Control: GLP-1RA-Based Therapies and Emerging Targets Beyond the Metabolic Axis.Journal of clinical medicine · 2026Review
- Cognitive-Enhancing Effects of Bioactive Compounds and Traditional Herbal Medicines in Elderly Patients with Metabolic Syndrome.Biomolecules · 2026Review
- Fibro-adipogenic progenitor cells from murine SMA muscles are intrinsically adipogenic.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- The progress and challenges of mesenchymal stromal cell-based therapy for diabetes and its complications.Biological research · 2026Review
- Time-restricted feeding in rodent obesity models: impact on body weights, lipid profile and glucoregulation.International journal of obesity (2005) · 2026Review
- Insulin resistance: mechanisms and therapeutic interventions.Molecular biomedicine · 2026Review
- Altered Molecular Regulation of TUG Is a Central Feature of Insulin-Resistant Human Adipose Tissue.Diabetes · 2026Article
42 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Anna SantoroDivision of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
Timothy E McGrawDepartment of Biochemistry, Weill Medical College of Cornell University, New York, NY 10065, USA. Electronic address: temcgraw@med.cornell.edu.
Barbara B KahnDivision of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA. Electronic address: bkahn@bidmc.harvard.edu.
Beth Israel Deaconess Medical Center · USCornell University · US
Funding
Translational Research CoreP30DK020541 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI STREAMSON C CHUA · 2015 to 2026
$27.7MINTEGRATED ENDOCRINE &METABOLIC RESEARCH TRAININGT32DK007516 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI BARBARA B. KAHN · 1986 to 2026
$6.8MRegulation of the biosynthesis of a novel class of anti-diabetic lipidsR01DK106210 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI KAHN, BARBARA B., SAGHATELIAN, ALAN · 2016 to 2024
$6.6MINSULIN REGULATED MEMBRANE TRAFFICKINGR01DK052852 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI MCGRAW, TIMOTHY E · 1997 to 2016
$6.1MGLUCOSE TRANSPORTER REGULATION IN OBESITY AND DIABETESR01DK043051 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI KAHN, BARBARA B. · 1992 to 2020
$4.4MGIP receptor: The role of post-activation receptor behavior for the incretin effectR01DK118342 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI MCGRAW, TIMOTHY E · 2018 to 2021
$1.9MInsulin control of GLUT4 traffic to the plasma membrane of adipocytesR01DK125699 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI MCGRAW, TIMOTHY E · 2020 to 2023
$1.8MInsulin Regulated Membrane TraffickingR56DK052852 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI MCGRAW, TIMOTHY E · 2017 to 2017
$254kNIDDK NIH HHS P30 DK020541NIDDK NIH HHS R01 DK043051NIDDK NIH HHS R01 DK052852NIDDK NIH HHS R01 DK106210NIDDK NIH HHS R01 DK118342NIDDK NIH HHS R01 DK125699NIDDK NIH HHS R56 DK052852NIDDK NIH HHS T32 DK007516
Abstract
On this 100
Indexed as
AdipocytesAnimalsBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsDiabetes Mellitus, Type 2Energy MetabolismGlucoseGlucose Transporter Type 4HumansInsulinInsulin ResistanceBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsGlucoseGlucose Transporter Type 4Insulin
Identifiers
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.