Evidence map›Paper›PMID 33826843›Full record

ArticleACS infectious diseases2021

Enzymatic β-Oxidation of the Cholesterol Side Chain in

Tianao Yuan, Joshua M Werman, Xingyu Yin, Meng Yang, Miguel Garcia-Diaz, Nicole S Sampson

Open access · bronzeAbstract read
In one paragraph

Article in ACS infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Tianao YuanDepartment of Chemistry, Stony Brook University, Stony Brook, New York 11794-3400, United States.ORCID 0000-0002-4700-8654
Joshua M WermanDepartment of Chemistry, Stony Brook University, Stony Brook, New York 11794-3400, United States.ORCID 0000-0002-8521-7369
Xingyu YinBiochemistry and Structural Biology Graduate Program, Stony Brook University, Stony Brook, New York 11794-5215, United States.ORCID 0000-0003-3832-0547
Meng YangDepartment of Chemistry, Stony Brook University, Stony Brook, New York 11794-3400, United States.ORCID 0000-0002-1371-5844
Miguel Garcia-DiazDepartment of Pharmacological Sciences, Stony Brook University, Stony Brook, New York 11794-8651, United States.ORCID 0000-0003-1605-6861
Nicole S SampsonDepartment of Chemistry, Stony Brook University, Stony Brook, New York 11794-3400, United States.ORCID 0000-0002-2835-7760
Stony Brook University · US

Funding

Validating cholesterol-mediated Mycobacterium tuberculosis resistance to oxidative stress as a drug targetR01AI134054 · NIAID · STATE UNIVERSITY NEW YORK STONY BROOK · PI SAMPSON, NICOLE S · 2017 to 2021
$2.0M
NIAID NIH HHS R01 AI134054
6 · The paper itself

Abstract

The unique ability of

Indexed as

Mycobacterium tuberculosisCholesterolCoenzyme AEnoyl-CoA HydrataseOxidation-ReductionCholesterolCoenzyme AEnoyl-CoA HydratasecatabolismcholesterolMycobacterium tuberculosisRv3502cRv3538stereochemistry

Identifiers

PMID33826843
PMCPMC8204306
OpenAlexW3150546681

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.