Evidence map›Paper›PMID 33826799›Full record

ArticleAngewandte Chemie (International ed. in English)2021

XFEL Crystal Structures of Peroxidase Compound II.

Hanna Kwon, Jaswir Basran, Chinar Pathak, Mahdi Hussain, Samuel L Freeman, Alistair J Fielding, Anna J Bailey, Natalia Stefanou, Hazel A Sparkes, Takehiko Tosha and 12 more

Open access · hybridAbstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Stabilization of the Ferryl═Oxoheme Form ofJournal of the American Chemical Society · 2025
    Article
  7. Article
  8. Globin ferryl species: what is the nature of the protonation event at pH < 5?Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Structural Characterization ofInternational journal of molecular sciences · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Serial femtosecond crystallography.Nature reviews. Methods primers · 2022
    Article
  17. Review
  18. Review
  19. Review
  20. Aspartate or arginine? Validated redox state X-ray structures elucidate mechanistic subtleties of FeJournal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 7 institutions in 2 countries.

Hanna KwonSchool of Chemistry, University of Bristol, Cantock's Close, Bristol, BS8 1TS, UK.ORCID 0000-0001-6941-4808
Jaswir BasranDepartment of Molecular and Cell Biology and Leicester Institute of Structural and Chemical Biology, University of Leicester, Lancaster Road, Leicester, LE1 7RH, UK.ORCID 0000-0003-2273-7348
Chinar PathakDepartment of Molecular and Cell Biology and Leicester Institute of Structural and Chemical Biology, University of Leicester, Lancaster Road, Leicester, LE1 7RH, UK.
Mahdi HussainDepartment of Molecular and Cell Biology and Leicester Institute of Structural and Chemical Biology, University of Leicester, Lancaster Road, Leicester, LE1 7RH, UK.
Samuel L FreemanSchool of Chemistry, University of Bristol, Cantock's Close, Bristol, BS8 1TS, UK.
Alistair J FieldingCentre for Natural Products Discovery, Pharmacy and Biomolecular Sciences, Liverpool John Moores University, James Parsons Building, Byrom Street, Liverpool, L3 3AF, UK.
Anna J BaileySchool of Chemistry, University of Bristol, Cantock's Close, Bristol, BS8 1TS, UK.
Natalia StefanouSchool of Chemistry, University of Bristol, Cantock's Close, Bristol, BS8 1TS, UK.
Hazel A SparkesSchool of Chemistry, University of Bristol, Cantock's Close, Bristol, BS8 1TS, UK.
Takehiko ToshaRIKEN SPring-8 Center, 1-1-1 Kouto, Sayo, Hyogo, 679-5148, Japan.
Keitaro YamashitaRIKEN SPring-8 Center, 1-1-1 Kouto, Sayo, Hyogo, 679-5148, Japan.
Kunio HirataRIKEN SPring-8 Center, 1-1-1 Kouto, Sayo, Hyogo, 679-5148, Japan.
Hironori MurakamiJapan Synchrotron Radiation Research Institute, 1-1-1 Kouto, Sayo, Hyogo, 679-5198, Japan.
Go UenoRIKEN SPring-8 Center, 1-1-1 Kouto, Sayo, Hyogo, 679-5148, Japan.
Hideo AgoRIKEN SPring-8 Center, 1-1-1 Kouto, Sayo, Hyogo, 679-5148, Japan.
Kensuke TonoJapan Synchrotron Radiation Research Institute, 1-1-1 Kouto, Sayo, Hyogo, 679-5198, Japan.
Masaki YamamotoRIKEN SPring-8 Center, 1-1-1 Kouto, Sayo, Hyogo, 679-5148, Japan.
Hitomi SawaiGraduate School of Life Science, University of Hyogo, 3-2-1 Kouto, Kamigori-cho, Ako-gun, Hyogo, 678-1297, Japan.
Yoshitsugu ShiroGraduate School of Life Science, University of Hyogo, 3-2-1 Kouto, Kamigori-cho, Ako-gun, Hyogo, 678-1297, Japan.
Hiroshi SugimotoRIKEN SPring-8 Center, 1-1-1 Kouto, Sayo, Hyogo, 679-5148, Japan.
Emma L RavenSchool of Chemistry, University of Bristol, Cantock's Close, Bristol, BS8 1TS, UK.ORCID 0000-0002-1643-8694
Peter C E MoodyDepartment of Molecular and Cell Biology and Leicester Institute of Structural and Chemical Biology, University of Leicester, Lancaster Road, Leicester, LE1 7RH, UK.ORCID 0000-0003-1762-9238
SPring-8 · JPUniversity of Bristol · GBUniversity of Leicester · GBJapan Synchrotron Radiation Research Institute · JPUniversity of Hyogo · JPLiverpool John Moores University · GBMRC Laboratory of Molecular Biology · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxygen activation in all heme enzymes requires the formation of high oxidation states of iron, usually referred to as ferryl heme. There are two known intermediates: Compound I and Compound II. The nature of the ferryl heme-and whether it is an Fe

Indexed as

LasersCrystallography, X-RayModels, MolecularPeroxidasesPeroxidaseshemeheme proteinsperoxidase

Identifiers

PMID33826799
PMCPMC8251747
OpenAlexW3142524923

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.