Evidence map›Paper›PMID 33826684›Full record

ArticleVaccine: X2019

The autotransporter protein BatA is a protective antigen against lethal aerosol infection with

Eric R Lafontaine, Zhenhai Chen, Maria Cristina Huertas-Diaz, Jeremy S Dyke, Tomislav P Jelesijevic, Frank Michel, Robert J Hogan, Biao He

Open access · hybridAbstract read
In one paragraph

Article in Vaccine: X, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Isolation and Purification of theArchives of Razi Institute · 2025
    Article
  5. Review
  6. Review
  7. Review
  8. LVS ΔmBio · 2024
    Article
  9. Vaccines · 2024
    Review
  10. Article
  11. Article
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  13. Review
  14. Recent Progress inPathogens (Basel, Switzerland) · 2021
    Review
  15. Current Advances inCells · 2020
    Review
  16. Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Eric R LafontaineDepartment of Infectious Diseases, University of Georgia College of Veterinary Medicine, Athens, GA 30602, USA.
Zhenhai ChenDepartment of Infectious Diseases, University of Georgia College of Veterinary Medicine, Athens, GA 30602, USA.
Maria Cristina Huertas-DiazDepartment of Infectious Diseases, University of Georgia College of Veterinary Medicine, Athens, GA 30602, USA.
Jeremy S DykeDepartment of Infectious Diseases, University of Georgia College of Veterinary Medicine, Athens, GA 30602, USA.
Tomislav P JelesijevicDepartment of Infectious Diseases, University of Georgia College of Veterinary Medicine, Athens, GA 30602, USA.
Frank MichelDepartment of Veterinary Biosciences and Diagnostic Imaging, University of Georgia College of Veterinary Medicine, Athens, GA 30602, USA.
Robert J HoganDepartment of Infectious Diseases, University of Georgia College of Veterinary Medicine, Athens, GA 30602, USA.
Biao HeDepartment of Infectious Diseases, University of Georgia College of Veterinary Medicine, Athens, GA 30602, USA.
University of Georgia · US

Funding

A Novel Vaccine for Burkholderia pseudomallei and Burkholderia malleiR01AI117290 · NIAID · UNIVERSITY OF GEORGIA · PI HE, BIAO, HOGAN, ROBERT J · 2017 to 2020
$2.6M
NIAID NIH HHS R01 AI117290
6 · The paper itself

Abstract

background

methodsVaccines (subunit and vectored) containing the surface-exposed passenger domain of the conserved

resultsA single dose of recombinant Parainfluenza Virus 5 (PIV5) expressing BatA provided 74% and 60% survival in mice infected with

conclusionOur study indicates that the autotransporter BatA is a valuable target for developing countermeasures against

Indexed as

Autotransporter protective antigenGlandersLethal aerosol challengeMelioidosisPIV5 vaccine vectorTier 1 select agent

Identifiers

PMID33826684
PMCPMC6668238
OpenAlexW2906340924

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.