Evidence map›Paper›PMID 33826422›Full record

ArticleHealth security

Genomics in Patient Care and Workforce Decisions in High-Level Isolation Units: A Survey of Healthcare Workers.

Jennifer E Gerber, Gail Geller, Angie Boyce, Lisa L Maragakis, Brian T Garibaldi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Health security. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Ethical Preparedness for U.S. Biocontainment Units.Journal of bioethical inquiry · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jennifer E GerberJennifer E. Gerber, PhD, MSc, was a PhD Student and Graduate Research Assistant at the time of the study, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD. She is now an Epidemiologist, RTI International, Washington, DC. Gail Geller, ScD, MHS, is a Professor, Department of Health, Behavior, and Society and Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health; Professor, Department of Medicine, Johns Hopkins School of Medicine; and Director of Education Initiatives and Core Faculty, Berman Institute of Bioethics, Johns Hopkins University; all in Baltimore, MD. Angie Boyce, PhD, is a Science and Technology Policy Fellow, American Association for the Advancement of Science, Washington, DC. Lisa L. Maragakis, MD, MPH, is an Associate Professor of Medicine and Executive Director, Johns Hopkins Biocontainment Unit; and Brian T. Garibaldi, MD, MEHP, is an Associate Professor of Medicine, Physiology, and Informatics, Division of Pulmonary and Critical Care, and Director, Johns Hopkins Biocontainment Unit; both in the Johns Hopkins School of Medicine, Baltimore, MD. Lisa L. Maragakis is also Senior Director of Infection Prevention, The Johns Hopkins Health System, Baltimore, MD.
Gail GellerJennifer E. Gerber, PhD, MSc, was a PhD Student and Graduate Research Assistant at the time of the study, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD. She is now an Epidemiologist, RTI International, Washington, DC. Gail Geller, ScD, MHS, is a Professor, Department of Health, Behavior, and Society and Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health; Professor, Department of Medicine, Johns Hopkins School of Medicine; and Director of Education Initiatives and Core Faculty, Berman Institute of Bioethics, Johns Hopkins University; all in Baltimore, MD. Angie Boyce, PhD, is a Science and Technology Policy Fellow, American Association for the Advancement of Science, Washington, DC. Lisa L. Maragakis, MD, MPH, is an Associate Professor of Medicine and Executive Director, Johns Hopkins Biocontainment Unit; and Brian T. Garibaldi, MD, MEHP, is an Associate Professor of Medicine, Physiology, and Informatics, Division of Pulmonary and Critical Care, and Director, Johns Hopkins Biocontainment Unit; both in the Johns Hopkins School of Medicine, Baltimore, MD. Lisa L. Maragakis is also Senior Director of Infection Prevention, The Johns Hopkins Health System, Baltimore, MD.
Angie BoyceJennifer E. Gerber, PhD, MSc, was a PhD Student and Graduate Research Assistant at the time of the study, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD. She is now an Epidemiologist, RTI International, Washington, DC. Gail Geller, ScD, MHS, is a Professor, Department of Health, Behavior, and Society and Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health; Professor, Department of Medicine, Johns Hopkins School of Medicine; and Director of Education Initiatives and Core Faculty, Berman Institute of Bioethics, Johns Hopkins University; all in Baltimore, MD. Angie Boyce, PhD, is a Science and Technology Policy Fellow, American Association for the Advancement of Science, Washington, DC. Lisa L. Maragakis, MD, MPH, is an Associate Professor of Medicine and Executive Director, Johns Hopkins Biocontainment Unit; and Brian T. Garibaldi, MD, MEHP, is an Associate Professor of Medicine, Physiology, and Informatics, Division of Pulmonary and Critical Care, and Director, Johns Hopkins Biocontainment Unit; both in the Johns Hopkins School of Medicine, Baltimore, MD. Lisa L. Maragakis is also Senior Director of Infection Prevention, The Johns Hopkins Health System, Baltimore, MD.
Lisa L MaragakisJennifer E. Gerber, PhD, MSc, was a PhD Student and Graduate Research Assistant at the time of the study, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD. She is now an Epidemiologist, RTI International, Washington, DC. Gail Geller, ScD, MHS, is a Professor, Department of Health, Behavior, and Society and Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health; Professor, Department of Medicine, Johns Hopkins School of Medicine; and Director of Education Initiatives and Core Faculty, Berman Institute of Bioethics, Johns Hopkins University; all in Baltimore, MD. Angie Boyce, PhD, is a Science and Technology Policy Fellow, American Association for the Advancement of Science, Washington, DC. Lisa L. Maragakis, MD, MPH, is an Associate Professor of Medicine and Executive Director, Johns Hopkins Biocontainment Unit; and Brian T. Garibaldi, MD, MEHP, is an Associate Professor of Medicine, Physiology, and Informatics, Division of Pulmonary and Critical Care, and Director, Johns Hopkins Biocontainment Unit; both in the Johns Hopkins School of Medicine, Baltimore, MD. Lisa L. Maragakis is also Senior Director of Infection Prevention, The Johns Hopkins Health System, Baltimore, MD.
Brian T GaribaldiJennifer E. Gerber, PhD, MSc, was a PhD Student and Graduate Research Assistant at the time of the study, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD. She is now an Epidemiologist, RTI International, Washington, DC. Gail Geller, ScD, MHS, is a Professor, Department of Health, Behavior, and Society and Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health; Professor, Department of Medicine, Johns Hopkins School of Medicine; and Director of Education Initiatives and Core Faculty, Berman Institute of Bioethics, Johns Hopkins University; all in Baltimore, MD. Angie Boyce, PhD, is a Science and Technology Policy Fellow, American Association for the Advancement of Science, Washington, DC. Lisa L. Maragakis, MD, MPH, is an Associate Professor of Medicine and Executive Director, Johns Hopkins Biocontainment Unit; and Brian T. Garibaldi, MD, MEHP, is an Associate Professor of Medicine, Physiology, and Informatics, Division of Pulmonary and Critical Care, and Director, Johns Hopkins Biocontainment Unit; both in the Johns Hopkins School of Medicine, Baltimore, MD. Lisa L. Maragakis is also Senior Director of Infection Prevention, The Johns Hopkins Health System, Baltimore, MD.

Funding

Ethical, Legal and Social Issues for Precision Medicine and Infectious DiseaseRM1HG009038 · NHGRI · JOHNS HOPKINS UNIVERSITY · PI GELLER, GAIL, KAHN, JEFFREY P. · 2016 to 2020
$4.8M
NHGRI NIH HHS RM1 HG009038
6 · The paper itself

Abstract

The impact of host genomics on an individual's susceptibility, immune response, and risk of severe outcomes for a given infectious pathogen is increasingly recognized. As we uncover the links between host genomics and infectious disease, a number of ethical, legal, and social issues need to be considered when using that information in clinical practice or workforce decisions. We conducted a survey of the clinical staff at 10 federally funded Regional Ebola and Other Special Pathogen Treatment Centers to understand their views regarding the ethical, legal, and social issues related to host genomics and the administrative and clinical functions of high-level isolation units. Respondents overwhelmingly agreed that genomics could provide valuable information to identify patients and employees at higher risk for poor outcomes from highly infectious diseases. However, there was considerable disagreement about whether such data should inform the allocation of scarce resources or determine treatment decisions. While most respondents supported a confidential employer-based genomic testing system to inform individual employees about risk, respondents disagreed about whether such information should be used in staffing models. Respondents who thought genomic information would be valuable for patient treatment were more willing to undergo genetic testing for staffing purposes. Most respondents felt they would benefit from additional training to better interpret results from genetic testing. Although this study was completed before the COVID-19 pandemic, the responses provide a baseline assessment of provider attitudes that can inform policy during the current pandemic and in future infectious disease outbreaks.

Indexed as

Attitude of Health PersonnelBiomedical ResearchCOVID-19Disease OutbreaksGenomicsHealth PersonnelHemorrhagic Fever, EbolaHumansBiocontainmentBioethicsCOVID-19ELSIEpidemic Management/responseGenomicsResource allocation

Identifiers

PMID33826422
PMCPMC8217591

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.