Evidence map›Paper›PMID 33826089›Full record

ArticleAdvances in therapy2021

Sensitivity, Specificity and Accuracy of a Novel EEG-Based Objective Test, the Cognalyzer

Alison C McDonald, Israel Gasperin Haaz, Weikai Qi, David C Crowley, Najla Guthrie, Malkanthi Evans, Dan Bosnyak

2 registry-linked trialsAbstract read
In one paragraph

Article in Advances in therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07680608 completednot on this mapstarted 2025, after this paper: background citation

Neurophysiological, Sleep-Related, and Mood Effects of a Cosmetic Shampoo and Conditioner Regimen in Adults With Scalp Discomfort and Sleep Difficulty: A Pilot EEG-Based Observational Study

TypeobservationalSponsorZentrela Inc.Ran2025 to 2026Enrolled21ConditionsDandruffArmsCosmetic Shampoo and Conditioner Regimen
NCT07740135 enrolling by invitationnot on this mapstarted 2026, after this paper: background citation

Mood and Well-Being Following 12 Weeks of Daily Centrum Silver Multivitamin Supplementation in Adults Between 40-60: A Neurophysiological EEG Study Using the Cognalyzer EEG Analysis

Typeobservational_patient_registrySponsorZentrela Inc.Ran2026 to 2026Enrolled30ConditionsWell-being/Quality of LifeArmsCentrum Silver Adult Multivitamin UPC 62107535670
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Adolescents are more sensitive than adults to acute behavioral and cognitive effects of THC.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
    Trial
  2. Article
  3. Cannabis and Driving.Frontiers in psychiatry · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alison C McDonaldKGK Science Inc., 255 Queens Ave, London, ON, N6A 5R8, Canada.
Israel Gasperin HaazZentrela Inc., Suite B21, 175 Longwood Rd S, Hamilton, ON, L8P 0A1, Canada.
Weikai QiZentrela Inc., Suite B21, 175 Longwood Rd S, Hamilton, ON, L8P 0A1, Canada.
David C CrowleyKGK Science Inc., 255 Queens Ave, London, ON, N6A 5R8, Canada.
Najla GuthrieKGK Science Inc., 255 Queens Ave, London, ON, N6A 5R8, Canada.
Malkanthi EvansKGK Science Inc., 255 Queens Ave, London, ON, N6A 5R8, Canada.
Dan BosnyakZentrela Inc., Suite B21, 175 Longwood Rd S, Hamilton, ON, L8P 0A1, Canada. dbosnyak@zentrela.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCurrent standards for identifying recent cannabis use are based on body fluid testing. The Cognalyzer

methodsSeventy-five participants, aged 19-55 years, were enrolled, and oral fluid samples were collected pre-cannabis inhalation. EEG and subjective drug effects questionnaire (DEQ) were administered pre- and post-ad libitum cannabis inhalation. Fifty participants remained in the clinic for 4 h post-inhalation. Blinded analyses of the EEG files were conducted by Zentrela Inc. using two versions (V1 and V2) of the Cognalyzer

resultsThe two versions of the Cognalyzer

conclusionThe Cognalyzer

Indexed as

CannabisMarijuana SmokingAdultDronabinolElectroencephalographyHumansMiddle AgedSalivaSensitivity and SpecificityYoung AdultDronabinolCannabisCognalyzer®EEGInhalationSmokingTHCVaping

Identifiers

PMID33826089
PMCPMC8024442

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.