Evidence map›Paper›PMID 33826022›Full record

ArticleAIDS and behavior2021

Acceptability and Feasibility of Pharmacy-Based Delivery of Pre-Exposure Prophylaxis in Kenya: A Qualitative Study of Client and Provider Perspectives.

Stephanie D Roche, Njeri Wairimu, Peter Mogere, Kevin Kamolloh, Josephine Odoyo, Zachary A Kwena, Elizabeth A Bukusi, Kenneth Ngure, Jared M Baeten, Katrina F Ortblad

Open access · hybridAbstract read
In one paragraph

Article in AIDS and behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 2 pooled it
12.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Stephanie D RocheDepartment of Global Health, University of Washington, 325 Ninth Avenue, Seattle, Washington, 98104, USA. sroche@uw.edu.ORCID http://orcid.org/0000-0001-7569-3241
Njeri WairimuPartners in Health and Research Development, Nairobi, Kenya.
Peter MogerePartners in Health and Research Development, Nairobi, Kenya.
Kevin KamollohCenter for Microbiology Research, Kenya Medical Research Institute, Kisumu, Kenya.
Josephine OdoyoCenter for Microbiology Research, Kenya Medical Research Institute, Kisumu, Kenya.
Zachary A KwenaCenter for Microbiology Research, Kenya Medical Research Institute, Kisumu, Kenya.
Elizabeth A BukusiDepartment of Global Health, University of Washington, 325 Ninth Avenue, Seattle, Washington, 98104, USA.
Kenneth NgurePartners in Health and Research Development, Nairobi, Kenya.
Jared M BaetenDepartment of Global Health, University of Washington, 325 Ninth Avenue, Seattle, Washington, 98104, USA.
Katrina F OrtbladDepartment of Global Health, University of Washington, 325 Ninth Avenue, Seattle, Washington, 98104, USA.
University of Washington · USKenya Medical Research Institute · KEPartners for Health and Development in Africa · KEJomo Kenyatta University of Agriculture and Technology · KE

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI EDWIN ROBERTO ORELLANA · 1988 to 2026
$104.9M
Pharmacy delivery to expand the reach of PrEP in KenyaR34MH120106 · NIMH · UNIVERSITY OF WASHINGTON · PI ORTBLAD, KATRINA FRANCES · 2019 to 2020
$605k
Peer PrEP referral + HIV self-test for PrEP initiation among young Kenyan womenK99MH121166 · NIMH · UNIVERSITY OF WASHINGTON · PI ORTBLAD, KATRINA FRANCES · 2020 to 2020
$122k
National Institute of Allergy and Infectious Diseases P30AI027757NIAID NIH HHS P30 AI027757NIMH NIH HHS K99 MH121166NIMH NIH HHS K99MH121166NIMH NIH HHS R34 MH120106NIMH NIH HHS R34MH120106
6 · The paper itself

Abstract

As countries scale up pre-exposure prophylaxis (PrEP) for HIV prevention, diverse PrEP delivery models are needed to expand access to populations at HIV risk that are unwilling or unable to access clinic-based PrEP care. To identify factors that may influence implementation of retail pharmacy-based PrEP delivery in Kenya, we conducted in-depth interviews with 40 pharmacy clients, 16 pharmacy providers, 16 PrEP clients, and 10 PrEP providers from two provinces. Most participants expressed strong support for expanding PrEP to retail pharmacies, though conditioned their acceptance on assurances that care would be private, respectful, safe, and affordable. Participant-reported determinants of feasibility centered primarily on ensuring that the intervention is compatible with retail pharmacy operations (e.g., staffing levels, documentation requirements). Future research is needed to develop and test tailored packages of implementation strategies that are most effective at integrating PrEP delivery into routine pharmacy practice in Kenya and other high HIV prevalence settings.

Indexed as

Anti-HIV AgentsHIV InfectionsPharmaciesPharmacyPre-Exposure ProphylaxisFeasibility StudiesHumansKenyaAnti-HIV AgentsDifferentiated careHIV preventionImplementation scienceKenyaPre-exposure prophylaxis

Identifiers

PMID33826022
PMCPMC8602157
OpenAlexW3151546695

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.