Evidence map›Paper›PMID 33825963›Full record

ArticleCell and tissue research2021

Cul3 is required for normal development of the mammary gland.

Cristina M Cummings, Jeffrey D Singer

Abstract read
PubMed Publisher
In one paragraph

Article in Cell and tissue research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Role of DCAF8 in Mammary Ductal Elongation and Branching Morphogenesis.Journal of mammary gland biology and neoplasia · 2026
    Article
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Cristina M CummingsSchool of Natural Sciences and Mathematics, Stockton University, Galloway, NJ, USA.
Jeffrey D SingerDepartment of Biology, Portland State University, Portland, OR, USA. jsinger@pdx.edu.ORCID http://orcid.org/0000-0002-0654-3036
Portland State University · USStockton University · US

Funding

NIH HHS RO1GM082940Susan G. Komen BCTR0503636
6 · The paper itself

Abstract

Cullin 3 (Cul3) has recently been implicated in a multitude of different processes, including the oxidative stress response, autophagy, tumorigenesis, and differentiation. To investigate the role of Cul3 in mammary gland development, we created a mouse model system using Cre-lox targeting where Cul3 is specifically deleted from the mammary gland. Such MMTV-Cre Cul3

Indexed as

AnimalsCullin ProteinsDisease Models, AnimalFemaleGenotypeMammary Glands, AnimalMiceMice, KnockoutCul3 protein, mouseCullin ProteinsArborizationCul3Duct morphogenesisMammary gland developmentMouse model

Identifiers

PMID33825963
OpenAlexW3148178398

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.