Evidence map›Paper›PMID 33825574›Full record

ArticleNeurorehabilitation and neural repair2021

Resting State Connectivity Is Modulated by Motor Learning in Individuals After Stroke.

Sarah N Kraeutner, Cristina Rubino, Shie Rinat, Bimal Lakhani, Michael R Borich, Katie P Wadden, Lara A Boyd

Open access · hybridAbstract read
In one paragraph

Article in Neurorehabilitation and neural repair, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Sarah N KraeutnerUniversity of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0002-6552-6682
Cristina RubinoUniversity of British Columbia, Vancouver, British Columbia, Canada.
Shie RinatUniversity of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0003-2873-3153
Bimal LakhaniUniversity of British Columbia, Vancouver, British Columbia, Canada.
Michael R BorichEmory University, Atlanta, GA, USA.
Katie P WaddenMemorial University of Newfoundland, St. John's, Newfoundland, Canada.
Lara A BoydUniversity of British Columbia, Vancouver, British Columbia, Canada.
University of British Columbia · CAEmory University · USMemorial University of Newfoundland · CA

Funding

CIHR MOP-130269
6 · The paper itself

Abstract

objectiveActivity patterns across brain regions that can be characterized at rest (ie, resting-state functional connectivity [rsFC]) are disrupted after stroke and linked to impairments in motor function. While changes in rsFC are associated with motor recovery, it is not clear how rsFC is modulated by skilled motor practice used to promote recovery. The current study examined how rsFC is modulated by skilled motor practice after stroke and how changes in rsFC are linked to motor learning.

methodsTwo groups of participants (individuals with stroke and age-matched controls) engaged in 4 weeks of skilled motor practice of a complex, gamified reaching task. Clinical assessments of motor function and impairment, and brain activity (via functional magnetic resonance imaging) were obtained before and after training.

resultsWhile no differences in rsFC were observed in the control group, increased connectivity was observed in the sensorimotor network, linked to learning in the stroke group. Relative to healthy controls, a decrease in network efficiency was observed in the stroke group following training.

conclusionsFindings indicate that rsFC patterns related to learning observed after stroke reflect a shift toward a compensatory network configuration characterized by decreased network efficiency.

Indexed as

ConnectomePractice, PsychologicalAdultAgedAged, 80 and overCerebellumCerebral CortexFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedMotor SkillsNerve NetSensorimotor CortexStrokefunctional connectivitygraph theorymotor learningrs-fMRIstroke

Identifiers

PMID33825574
PMCPMC8135242
OpenAlexW3140527663

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.