Evidence map›Paper›PMID 33824908›Full record

ArticleMedicina clinica (English ed.)2021

Increased levels of ferritin on admission predicts intensive care unit mortality in patients with COVID-19.

Fuxue Deng, Lisha Zhang, Lyu Lyu, Ziwei Lu, Dengfeng Gao, Xiaorong Ma, Yonghong Guo, Rong Wang, Shouping Gong, Wei Jiang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Medicina clinica (English ed.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  20. Focusing COVID-19-associated mucormycosis: a major threat to immunocompromised COVID-19.Environmental science and pollution research international · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Fuxue DengDepartment of Cardiology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, China.
Lisha ZhangDepartment of Cardiology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, China.
Lyu LyuDepartment of Cardiology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, China.
Ziwei LuDepartment of Cardiology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, China.
Dengfeng GaoDepartment of Cardiology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, China.
Xiaorong MaDepartment of Hematology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, China.
Yonghong GuoDepartment of Infectious Diseases, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, China.
Rong WangDepartment of Cardiology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, China.
Shouping GongDepartment of Neurosurgery, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, China.
Wei JiangDepartment of Cardiology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to evaluate hyperferritinemia could be a predicting factor of mortality in hospitalized patients with coronavirus disease-2019 (COVID-19).

methodsA total of 100 hospitalized patients with COVID-19 in intensive care unit (ICU) were enrolled and classified into moderate (

resultsThe amount of ferritin was significantly higher in critical group compared with moderate and severe groups. The median of ferritin concentration was about three times higher in death group than survival group (1722.25 μg/L vs. 501.90 μg/L,

conclusionThe ferritin measured at admission may serve as an independent factor for predicting in-hospital mortality in patients with COVID-19 in ICU.

Indexed as

ALT, alanine aminotransferaseAOSD, adult-onset Still's diseaseAPTT, activated partial thromboplastin timeARDS, acute respiratory distress syndromeAST, aspartate aminotransferaseAUC, area under the curveBUN, urea nitrogenCAPS, catastrophic anti-phospholipid syndromeCHD, coronary heart diseasesCK-MB, creatine kinase-MBCOVID-19COVID-19, coronavirus disease-2019CRP, C-reactive proteinDBP, diastolic pressureDM, diabetes mellituseGFR, ovulated glomerular filtration rateFerritinFiO2, fraction of inspired oxygenHP, hypertensionHR, heart rateHs-TnI, high sensitive troponin IICU, intensive care unitIL, interleukinInflammation markersINR, international normalized ratioIQR, interquartile rangeMAS, macrophage activation syndromeMERS, Middle East respiratory syndromeMOF, multiple organ failureMortalityMV, mechanical ventilationNT-proBNP, N-terminal pro-B-type natriuretic peptidePaO2, partial pressure of arterial oxygenPCT, procalcitoninPTA, prothrombin activityPT, prothrombin timeRBC, red blood cellsROC, receiver operating characteristicRR, respiration rateRT-PCR, reverse transcription-polymerase chain reactionSARS-CoV-2SARS, severe acute respiratory syndromeSBP, systolic blood pressureSpO2, percutaneous oxygen saturationTNF, tumor necrosis factorTT, plasma thrombin timeWBC, white blood cells

Identifiers

PMID33824908
PMCPMC8016043

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.