ArticleCureus2021
Syphilitic Aortic Aneurysm: A Rare Entity in the Era of Antibiotics.
Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 9 citations in OpenAlex.
- Tertiary Syphilitic Aortitis Manifesting as Ascending Aortic Aneurysm and Dissection.JACC. Case reports · 2026Article
- A case of giant syphilitic Stanford type a aortic dissection with right pulmonary artery compression presenting as facial swelling.Journal of cardiothoracic surgery · 2025Article
- Syphilitic Aortitis Incidentally Detected by Fluorine-18 Fluorodeoxyglucose (18F-FDG) PET/CT.Cureus · 2025Article
- Mechanisms of Neurosyphilis-Induced Dementia: Insights into Pathophysiology.Neurology international · 2024Review
- Article
- Challenges in the Diagnosis of Tertiary Syphilis: Case Report with Literature Review.International journal of environmental research and public health · 2022Review
- Contained rupture of an aortic arch aneurysm in a patient with syphilitic aortitis. A case report.Jornal vascular brasileiro · 2021Article
- Comment on Aortic Aneurysm: Dissection from the Root to Pelvis.Journal of medical ultrasoundArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A thoracic aortic aneurysm is a rare entity of tertiary syphilis in the era of antibiotics. The diagnosis of the aortic aneurysm due to tertiary syphilis may be challenging due to deceptive clinical presentation and rarity of the disease in the western world. We report the case of a 59-year-old man, who presents with worsening shortness of breath and was found to have a large ascending aortic aneurysm on computed tomography angiogram (CTA) of the chest. Further workup demonstrated a positive syphilis test. Untreated earlier stages of syphilis attribute to the development of the ascending aortic aneurysm. The patient was medically treated with IV penicillin and underwent surgical repair of the aortic aneurysm. Histopathology confirmed the diagnosis of syphilitic aortitis. Tertiary syphilis often presents several years after initial infection and usually after a latent phase, making it difficult to diagnose. Syphilitic aortic aneurysms may result in a high mortality rate in untreated patients. Therefore, a high index of suspicion is required for the early recognition of a syphilitic aortic aneurysm. Early treatment with antibiotic therapy and surgical repair of syphilitic aortic aneurysms can prevent life-threatening complications.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.