Evidence map›Paper›PMID 33824496›Full record

ReviewNature reviews. Microbiology2021

Bacillus subtilis biofilm formation and social interactions.

Sofia Arnaouteli, Natalie C Bamford, Nicola R Stanley-Wall, Ákos T Kovács

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 210 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
210citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

210 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Root colonization by beneficial rhizobacteria.FEMS microbiology reviews · 2024
    Pooled it
  2. Article
  3. Article
  4. CuBioactive materials · 2026
    Article
  5. Bacilli the most important biocontrol agent in Brazilian agriculture: from mechanisms of action to market adoption.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Review
  6. Article
  7. Diversity of biofilm architectures within the genusApplied and environmental microbiology · 2026
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. In Situ Electrochemical Monitoring ofChemical & biomedical imaging · 2026
    Article
  13. Article
  14. Article
  15. Small non-coding RNAMicrobiology spectrum · 2026
    Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

150 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sofia Arnaouteli *Division of Molecular Microbiology, School of Life Sciences, University of Dundee, Dundee, UK.
Natalie C Bamford *Division of Molecular Microbiology, School of Life Sciences, University of Dundee, Dundee, UK.ORCID http://orcid.org/0000-0003-1959-856X
Nicola R Stanley-WallDivision of Molecular Microbiology, School of Life Sciences, University of Dundee, Dundee, UK. n.r.stanleywall@dundee.ac.uk.ORCID http://orcid.org/0000-0002-5936-9721
Ákos T KovácsBacterial Interactions and Evolution Group, DTU Bioengineering, Technical University of Denmark, Kongens Lyngby, Denmark. atkovacs@dtu.dk.ORCID http://orcid.org/0000-0002-4465-1636

Funding

Biotechnology and Biological Sciences Research Council BB/P001335/1Biotechnology and Biological Sciences Research Council BB/R012415/1
6 · The paper itself

Abstract

Biofilm formation is a process in which microbial cells aggregate to form collectives that are embedded in a self-produced extracellular matrix. Bacillus subtilis is a Gram-positive bacterium that is used to dissect the mechanisms controlling matrix production and the subsequent transition from a motile planktonic cell state to a sessile biofilm state. The collective nature of life in a biofilm allows emergent properties to manifest, and B. subtilis biofilms are linked with novel industrial uses as well as probiotic and biocontrol processes. In this Review, we outline the molecular details of the biofilm matrix and the regulatory pathways and external factors that control its production. We explore the beneficial outcomes associated with biofilms. Finally, we highlight major advances in our understanding of concepts of microbial evolution and community behaviour that have resulted from studies of the innate heterogeneity of biofilms.

Indexed as

Bacillus subtilisBacterial ProteinsBiofilmsGene Expression Regulation, BacterialMicrobial InteractionsBacterial Proteins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.