Evidence map›Paper›PMID 33824426›Full record

ReviewThe ISME journal2021

Prokaryotic taxonomy and nomenclature in the age of big sequence data.

Philip Hugenholtz, Maria Chuvochina, Aharon Oren, Donovan H Parks, Rochelle M Soo

Abstract readReview
In one paragraph

Review in The ISME journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers.

0numbers the graph read from it
0cells of the map it votes in
102citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

102 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
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  5. Article
  6. Article
  7. Article
  8. Article
  9. Structure of theMicrobiology spectrum · 2026
    Article
  10. Article
  11. Article
  12. Genome-based reassessment ofCurrent research in microbial sciences · 2026
    Article
  13. Article
  14. Microbial Evolution and Systematics: Archaea and Bacteria.Progress in molecular and subcellular biology · 2026
    Review
  15. Article
  16. Addressing controversy inGut microbes · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Review

42 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Philip HugenholtzAustralian Centre for Ecogenomics, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD, Australia. p.hugenholtz@uq.edu.au.ORCID http://orcid.org/0000-0001-5386-7925
Maria ChuvochinaAustralian Centre for Ecogenomics, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD, Australia.
Aharon OrenDepartment of Plant and Environmental Sciences, The Alexander Silberman Institute of Life Sciences, The Edmond J. Safra campus, The Hebrew University of Jerusalem, Jerusalem, Israel.
Donovan H ParksAustralian Centre for Ecogenomics, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD, Australia.ORCID http://orcid.org/0000-0001-6662-9010
Rochelle M SooAustralian Centre for Ecogenomics, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD, Australia. r.soo@uq.edu.au.ORCID http://orcid.org/0000-0002-8927-2066

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The classification of life forms into a hierarchical system (taxonomy) and the application of names to this hierarchy (nomenclature) is at a turning point in microbiology. The unprecedented availability of genome sequences means that a taxonomy can be built upon a comprehensive evolutionary framework, a longstanding goal of taxonomists. However, there is resistance to adopting a single framework to preserve taxonomic freedom, and ever increasing numbers of genomes derived from uncultured prokaryotes threaten to overwhelm current nomenclatural practices, which are based on characterised isolates. The challenge ahead then is to reach a consensus on the taxonomic framework and to adapt and scale the existing nomenclatural code, or create a new code, to systematically incorporate uncultured taxa into the chosen framework.

Indexed as

GenomeProkaryotic CellsBiological Evolution

Identifiers

PMID33824426
PMCPMC8245423

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.