ArticleCommunications biology2021
Sweet taste of heavy water.
Article in Communications biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 40 citations in OpenAlex.
- Second-Generation of Deuterium-Substituted Glutamate Uptake Enhancers Exhibit Superior Drug-Like Properties in Preclinical Evaluation.ACS central science · 2026Article
- Heavy Water Remodels the DNA Energy Landscape to Stabilize Folded States and Slow Transitions.ACS physical chemistry Au · 2026Article
- Sweet and umami TAS1R receptors: from molecular recognition to physiological function.Chemical senses · 2026Review
- Constitutive activity of the sweet taste receptor: Heavy water sweetness and beyond.Protein science : a publication of the Protein Society · 2025Review
- Roles of Hydration in Protein-Ligand Binding: Passive or Active Participant?The journal of physical chemistry. A · 2025Article
- Hydration (HJournal of the American Chemical Society · 2025Article
- Deuteration may reduce the efficacy of dextromethorphan in treating agitation in Alzheimer's disease.Alzheimer's research & therapy · 2025Article
- The analgesic potential of heavy water.Nature biomedical engineering · 2025Article
- Unravelling non-adiabatic pathways in the mutual neutralization of hydronium and hydroxide.Nature chemistry · 2025Article
- Divergent Molecular Responses to Heavy Water inPlants (Basel, Switzerland) · 2024Article
- Designing chemical systems for precision deuteration of medicinal building blocks.Nature communications · 2024Article
- Testing the Conjecture That Quantum Processes Create Conscious Experience.Entropy (Basel, Switzerland) · 2024Article
- Staggered structural dynamic-mediated selective adsorption of HNature communications · 2024Article
- Elucidating the role of water in collagen self-assembly by isotopically modulating collagen hydration.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- DThe journal of physical chemistry. B · 2023Review
- Deuterium in drug discovery: progress, opportunities and challenges.Nature reviews. Drug discovery · 2023Review
- Effects of Water Deuteration on Thermodynamic and Structural Properties of Proteins and Biomembranes.The journal of physical chemistry. B · 2023Article
- Impact of lactisole on the time-intensity profile of selected sweeteners in dependence of the binding site.Food chemistry: X · 2022Article
- Viewpoints on the First Transatlantic GPCR Symposium for Early-Career Investigators.ACS pharmacology & translational science · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hydrogen to deuterium isotopic substitution has only a minor effect on physical and chemical properties of water and, as such, is not supposed to influence its neutral taste. Here we conclusively demonstrate that humans are, nevertheless, able to distinguish D
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.