Evidence map›Paper›PMID 33824236›Full record

ArticleAnnals of laboratory medicine2021

Granulocytic and Monocytic Myeloid-Derived Suppressor Cells are Functionally and Prognostically Different in Patients with Chronic Myeloid Leukemia.

Ari Ahn, Chan-Jeoung Park, Min-Sun Kim, Young-Uk Cho, Seongsoo Jang, Mi Hyun Bae, Jung-Hee Lee, Je-Hwan Lee, Kyung-Nam Koh, Ho Joon Im

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of laboratory medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Ari AhnDepartment of Laboratory Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID https://orcid.org/0000-0003-3408-767X
Chan-Jeoung ParkDepartment of Laboratory Medicine, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0003-4396-8348
Min-Sun KimDepartment of Laboratory Medicine, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0003-2061-5726
Young-Uk ChoDepartment of Laboratory Medicine, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0002-4403-8989
Seongsoo JangDepartment of Laboratory Medicine, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0002-0045-1747
Mi Hyun BaeDepartment of Laboratory Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Korea.ORCID https://orcid.org/0000-0003-2818-342X
Jung-Hee LeeDepartment of Internal Medicine, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0002-3127-0068
Je-Hwan LeeDepartment of Internal Medicine, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0002-7060-1675
Kyung-Nam KohDepartment of Pediatrics, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0002-6376-672X
Ho Joon ImDepartment of Pediatrics, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0001-8799-4068
Ulsan College · KRCatholic University of Korea · KRHanyang University Guri Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myeloid-derived suppressor cells (MDSCs) represent phenotypically heterogeneous populations that suppress tumor-specific T-cell responses. MDSCs are produced from myeloid precursors in emergent states and are increased in several hematologic malignancies. We evaluated the differences in the levels and prognostic significance of MDSCs according to the clinical status of chronic myeloid leukemia (CML). The percentages and numbers of granulocytic (g)MDSCs and monocytic (m)MDSCs in peripheral blood (PB) and bone marrow (BM) aspirates were determined by five-color flow cytometry (HLA-DR/CD11b/CD15/CD33/CD14). The median BM-gMDSC% and PB-gMDSC% of the CML group were lower than those of the complete hematologic response (CHR) and control groups (

Indexed as

Leukemia, Myelogenous, Chronic, BCR-ABL PositiveMyeloid-Derived Suppressor CellsGranulocytesHLA-DR AntigensHumansMonocytesHLA-DR AntigensChronic myeloid leukemiaComplete hematologic responseGranulocytic myeloid-derived suppressor cellMajor molecular responseMonocytic myeloid-derived suppressor cellPrognosis

Identifiers

PMID33824236
PMCPMC8041600
OpenAlexW3142685094

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.