Evidence map›Paper›PMID 33823860›Full record

ArticleJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance2021

Left and right ventricular strain using fast strain-encoded cardiovascular magnetic resonance for the diagnostic classification of patients with chronic non-ischemic heart failure due to dilated, hypertrophic cardiomyopathy or cardiac amyloidosis.

Henning Steen, Sorin Giusca, Moritz Montenbruck, Amit R Patel, Burkert Pieske, Andre Florian, Jennifer Erley, Sebastian Kelle, Grigorios Korosoglou

Open access · goldAbstract readComparative Study
In one paragraph

Article in Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
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  7. [Preliminary Study of Dilated Cardiomyopathy at a High Altitude Based on Cardiac Magnetic Resonance Feature Tracking].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025
    Article
  8. A Non-Invasive Approach to Pulmonary Hypertension.Journal of clinical medicine · 2025
    Review
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  19. Multi-parametric assessment of left ventricular hypertrophy using late gadolinium enhancement, T1 mapping and strain-encoded cardiovascular magnetic resonance.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2021
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Henning SteenDepartment of Cardiology, Marien Hospital Hamburg, Hamburg, Germany.
Sorin GiuscaDepartments of Cardiology, Vascular Medicine and Pneumology, GRN Academic Teaching Hospital Weinheim, Roentgenstrasse 1, 69469, Weinheim, Germany.
Moritz MontenbruckDepartment of Cardiology, Marien Hospital Hamburg, Hamburg, Germany.
Amit R PatelDepartment of Medicine, University of Chicago, Illinois, USA.
Burkert PieskeDepartment of Internal Medicine/Cardiology, German Heart Center Berlin, Berlin, Germany.
Andre FlorianDepartments of Cardiology, Angiology and Pneumology, Heidelberg University, Berlin, Germany.
Jennifer ErleyDepartment of Internal Medicine/Cardiology, German Heart Center Berlin, Berlin, Germany.
Sebastian KelleDepartment of Internal Medicine/Cardiology, German Heart Center Berlin, Berlin, Germany.
Grigorios KorosoglouDepartments of Cardiology, Vascular Medicine and Pneumology, GRN Academic Teaching Hospital Weinheim, Roentgenstrasse 1, 69469, Weinheim, Germany. gkorosoglou@hotmail.com.ORCID 0000-0002-6038-2253
Deutsches Herzzentrum der Charité · DESt. Marien Hospital · DEHeidelberg University · DEUniversity of Chicago · USUniversity of Mannheim · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo compare the ability of left ventricular (LV) and right ventricular (RV) strain measured by fast-strain encoded cardiovascular magnetic resonance (CMR) (fast-SENC) with LV- and RV-ejection fraction for the diagnostic classification of patients with different stages of chronic heart failure (stages A-D based on American College of Cardiology/American Heart Association guidelines) due to non-ischemic cardiomyopathies.

methodsOur study population consisted of 276 consecutive patients who underwent CMR for clinical reasons, and 19 healthy subjects. Wall motion score index and non-infarct related late gadolinium enhancement (LGE), LV ejection fraction (LVEF) and RV ejection fraction (RVEF) and global LV- and RV-longitudinal (GLS) and circumferential strain (GCS) based on fast-SENC acquisitions, were calculated in all subjects. The percentage of LV and RV myocardial segments with strain ≤ - 17% (%normal LV and RV myocardium) was determined in all subjects.

resultsLVEF and RVEF, LV-GLS, LV-GCS, RV-GLS, RV-GCS and %normal LV- and RV myocardium depressed with increasing heart failure stage (p < 0.001 for all by ANOVA). By multivariable analysis, %normal LV and RV myocardium exhibited closer associations to heart failure stages than LVEF and RVEF (r

conclusionsIn patients with non-ischemic cardiomyopathy, %normal LV and RV myocardium, by fast-SENC, enables improved identification of asymptomatic patients with subclinical LV-dysfunction. This technique may be useful for the early identification of such presumably healthy subjects at risk for heart failure and for monitoring LV and RV deformation during pharmacologic interventions in future studies.

Indexed as

Magnetic Resonance Imaging, CineStroke VolumeVentricular Function, LeftVentricular Function, RightAdultAgedAged, 80 and overAmyloidosisCardiomyopathy, DilatedCardiomyopathy, HypertrophicCase-Control StudiesEarly DiagnosisFemaleHeart FailureHumansMaleCardiac magnetic resonanceFast-strain-encoded MR (fast-SENC)Heart failureHypertrophyIschemic and non-ischemic cardiomyopathiesLate gadolinium enhancementMyocarditis

Identifiers

PMID33823860
PMCPMC8025329
OpenAlexW3150046878

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.