Evidence map›Paper›PMID 33823712›Full record

ArticleThe neuroradiology journal2021

Amide proton transfer imaging for differentiation of tuberculomas from high-grade gliomas: Preliminary experience.

Karthik Kulanthaivelu, Shumyla Jabeen, Jitender Saini, Sanita Raju, Atchayaram Nalini, Nishanth Sadashiva, Shashank Hegde, Narayana Krishna Rolla, Indrajit Saha, Netravathi M and 3 more

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In one paragraph

Article in The neuroradiology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Karthik KulanthaiveluDepartment of Neuroimaging and Interventional Radiology, National Institute of Mental Health and Neurosciences, India.ORCID https://orcid.org/0000-0002-1585-8769
Shumyla JabeenDepartment of Neuroimaging and Interventional Radiology, National Institute of Mental Health and Neurosciences, India.ORCID https://orcid.org/0000-0002-3816-4313
Jitender SainiDepartment of Neuroimaging and Interventional Radiology, National Institute of Mental Health and Neurosciences, India.
Sanita RajuDepartment of Neurology, National Institute of Mental Health and Neurosciences, India.
Atchayaram NaliniDepartment of Neurology, National Institute of Mental Health and Neurosciences, India.
Nishanth SadashivaDepartment of Neurosurgery, National Institute of Mental Health and Neurosciences, India.
Shashank HegdePhilips Healthcare, India.
Narayana Krishna RollaPhilips Health Systems, India.
Indrajit SahaPhilips Health Systems, India.
Netravathi MDepartment of Neurology, National Institute of Mental Health and Neurosciences, India.
Seena VengalilDepartment of Neurology, National Institute of Mental Health and Neurosciences, India.
Saikrishna SwaroopDepartment of Neurology, National Institute of Mental Health and Neurosciences, India.
Shilpa RaoDepartment of Neuropathology, National Institute of Mental Health and Neurosciences, India.
National Institute of Mental Health and Neurosciences · INPhilips (India) · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTuberculomas can occasionally masquerade as high-grade gliomas (HGG). Evidence from magnetisation transfer (MT) imaging suggests that there is lower protein content in the tuberculoma microenvironment. Building on the principles of chemical exchange saturation transfer and MT, amide proton transfer (APT) imaging generates tissue contrast as a function of the mobile amide protons in tissue's native peptides and intracellular proteins. This study aimed to further the understanding of tuberculomas using APT and to compare it with HGG.

methodTwenty-two patients (

resultsMTR

conclusionTuberculomas demonstrate lower MTR

Indexed as

GliomaTuberculomaAmidesBrainHumansMagnetic Resonance ImagingProtonsTumor MicroenvironmentAmidesProtonsAmide proton transfer imagingchemical exchange saturation transfermagnetisation transfer imagingtuberculoma

Identifiers

PMID33823712
PMCPMC8559025
OpenAlexW3149321093

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.