Evidence map›Paper›PMID 33823709›Full record

ArticleJournal of intensive care medicine2021

Extracorporeal Membrane Oxygenation in Patients With COVID-19: An International Multicenter Cohort Study.

Senta Jorinde Raasveld, Thijs S R Delnoij, Lars M Broman, Annemieke Oude Lansink-Hartgring, Greet Hermans, Erwin De Troy, Fabio S Taccone, Manuel Quintana Diaz, Franciska van der Velde, Dinis Dos Reis Miranda and 3 more

Open access · hybridAbstract readComparative StudyMulticenter Study
In one paragraph

Article in Journal of intensive care medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 10 institutions in 4 countries.

Senta Jorinde RaasveldDepartment of Intensive Care, Amsterdam University Medical Centers, Location Academic Medical Center (26066AMC), Amsterdam, the Netherlands.
Thijs S R DelnoijDepartment of Cardiology, 199236Maastricht University Medical Center, Maastricht, the Netherlands.
Lars M BromanDepartment of Physiology and Pharmacology, 59562Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0003-4124-4581
Annemieke Oude Lansink-HartgringDepartment of Critical Care, 10173University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.ORCID https://orcid.org/0000-0003-3641-9658
Greet HermansMedical Intensive Care Unit, Department of General Internal Medicine, 60182University Hospitals Leuven, KU Leuven, Herestraat, Leuven, Belgium.
Erwin De TroySurgical Adult Intensive Care Unit, Department of Intensive Care Medicine, University Hospitals Leuven, KU Leuven, Leuven, Belgium.
Fabio S TacconeDepartment of Intensive Care, 26659Université Libre de Bruxelles, Hôpital Erasme Bruxelles, Brussels, Belgium.
Manuel Quintana DiazDepartment of Intensive Care, 16268Hospital Universitario La Paz, Madrid, Spain.
Franciska van der VeldeDepartment of Intensive Care, 4501Leids University Medical Center, Leiden, the Netherlands.
Dinis Dos Reis MirandaDepartment of Intensive Care, 6984Erasmus Medical Center, University Medical Center Rotterdam, the Netherlands.
Erik ScholtenDepartment of Intensive Care, 6028St. Antonius Hospital, Nieuwegein, the Netherlands.
ETALON Study Group
Alexander P J VlaarDepartment of Intensive Care, Amsterdam University Medical Centers, Location Academic Medical Center (26066AMC), Amsterdam, the Netherlands.ORCID https://orcid.org/0000-0002-7398-3445
Amsterdam UMC Location University of Amsterdam · NLKU Leuven · BEErasmus MC · NLHospital Universitario La Paz · ESKarolinska Institutet · SELeiden University Medical Center · NLMaastricht University · NLSt. Antonius Ziekenhuis · NLUniversité Libre de Bruxelles · BEUniversity Medical Center Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo report and compare the characteristics and outcomes of COVID-19 patients on extracorporeal membrane oxygenation (ECMO) to non-COVID-19 acute respiratory distress syndrome (ARDS) patients on ECMO.

methodsWe performed an international retrospective study of COVID-19 patients on ECMO from 13 intensive care units from March 1 to April 30, 2020. Demographic data, ECMO characteristics and clinical outcomes were collected. The primary outcome was to assess the complication rate and 28-day mortality; the secondary outcome was to compare patient and ECMO characteristics between COVID-19 patients on ECMO and non-COVID-19 related ARDS patients on ECMO (non-COVID-19; January 1, 2018 until July 31, 2019).

resultsDuring the study period 71 COVID-19 patients received ECMO, mostly veno-venous, for a median duration of 13 days (IQR 7-20). ECMO was initiated at 5 days (IQR 3-10) following invasive mechanical ventilation. Median PaO

conclusionsNo significant differences in outcomes were found between COVID-19 patients on ECMO and non-COVID-19 ARDS patients on ECMO. This suggests that ECMO could be considered as a supportive therapy in case of refractory respiratory failure in COVID-19.

Indexed as

COVID-19Extracorporeal Membrane OxygenationRespiratory Distress SyndromeCohort StudiesFemaleHumansInternationalityMaleMiddle AgedRetrospective StudiesARDSCOVID-19ECMOsurvival

Identifiers

PMID33823709
PMCPMC8267077
OpenAlexW3145060000

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.