Evidence map›Paper›PMID 33823627›Full record

ArticleGlobal spine journal2023

Evaluation of Adjacent Segment With Pre-Existing Degeneration Using the Cerebrospinal Fluid Occlusion Sign on MRI Before Posterior Lumbar Fusion: A Multi-Center Observational Cohort Study.

Zhuoran Sun, Zhuofu Li, Yang Guo, Weishi Li, Xin Chen, Shugang Li, Jianxiong Shen, Longtao Qi, Yao Zhao, Chunde Li and 3 more

Open access · goldAbstract read
In one paragraph

Article in Global spine journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Zhuoran SunOrthopaedic Department of 48432Peking University Third Hospital, Beijing, China.
Zhuofu LiOrthopaedic Department of 48432Peking University Third Hospital, Beijing, China.
Yang GuoOrthopaedic Department of 48432Peking University Third Hospital, Beijing, China.
Weishi LiOrthopaedic Department of 48432Peking University Third Hospital, Beijing, China.ORCID 0000-0001-9512-5436
Xin ChenOrthopaedic Department of 34732Peking Union Medical College Hospital, Beijing, China.
Shugang LiOrthopaedic Department of 34732Peking Union Medical College Hospital, Beijing, China.ORCID 0000-0002-1737-9796
Jianxiong ShenOrthopaedic Department of 34732Peking Union Medical College Hospital, Beijing, China.ORCID 0000-0001-7172-9550
Longtao QiOrthopaedic Department of 66482Peking University First Hospital, Beijing, China.
Yao ZhaoOrthopaedic Department of 66482Peking University First Hospital, Beijing, China.
Chunde LiOrthopaedic Department of 66482Peking University First Hospital, Beijing, China.
Di ZhuOrthopaedic Department of 105738Beijing Tiantan Hospital, Beijing, China.
Jichao ZhuOrthopaedic Department of 105738Beijing Tiantan Hospital, Beijing, China.
Baoge LiuOrthopaedic Department of 105738Beijing Tiantan Hospital, Beijing, China.ORCID 0000-0002-2156-0870
Peking University · CNBeijing Tian Tan Hospital · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designProspective cohort study.

objectiveTo evaluate whether pre-existing adjacent spinal canal stenosis (SCS) is associated with short-term outcomes after lumbar fusion surgery.

methodsWe included patients with lumbar spinal stenosis treated surgically between July 2015 and December 2017 at 4 centers. All patients had the same pathology, with L4-S1 as the culprit sections. Patients were divided into 2 groups based on the cerebrospinal fluid occlusion sign on MRI at the adjacent L3/4 level. Patients without SCS (grade 0) and with mild SCS (grade 1) were classified into the non-stenosis (NS) and mild stenosis (MS) groups, respectively. All patients underwent PLIF and completed at least 1-year follow-up. The incidence of adjacent segment degeneration (ASDeg) and clinical outcomes were compared between the 2 groups.

resultsA total of 308 patients (NS, 156; MS, 152) met the inclusion criteria. The incidence of ASDeg in the NS group (n = 40, 25.6%) was significantly lower than that in the MS group (n = 74, 48.7%;

conclusionsThe cerebrospinal fluid occlusion sign on MRI is valuable for evaluating the adjacent segment with pre-existing degeneration. Patients with mild SCS in adjacent segments were more likely to have ASDeg, and the most frequent type of ASDeg was the SCS-aggravated type at early follow-up.

Indexed as

adjacent segment degenerationcerebrospinal fluid occlusionpre-existing degenerationspinal canal stenosis

Identifiers

PMID33823627
PMCPMC10240597
OpenAlexW3145898056

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.