Evidence map›Paper›PMID 33823209›Full record

SynthesisBrazilian journal of anesthesiology (Elsevier)

Identification and economic burden of main adverse events of nerve injuries caused by regional anesthesia: a systematic review.

Stefano Calciolari, Laura Guadalupe González-Ortiz, Francesco Mongelli, Laura Cantini, Xavier Capdevila, Davide La Regina, Andrea Saporito

Open access · diamondAbstract readSystematic Review
In one paragraph

Synthesis in Brazilian journal of anesthesiology (Elsevier). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Anesthesia services management, economics, and new technologies.Brazilian journal of anesthesiology (Elsevier)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Stefano CalciolariUniversità di Milano-Bicocca, Department of Economics, Management and Statistics (DEMS), Milano, Italy; Università della Svizzera Italiana, Institute of Economics (IdEP), Lugano, Switzerland.
Laura Guadalupe González-OrtizUniversità della Svizzera Italiana, Institute of Economics (IdEP), Lugano, Switzerland.
Francesco MongelliOspedale Regionale di Lugano, Lugano, Switzerland. Electronic address: francesco.mongelli@mail.com.
Laura CantiniOspedale Regionale di Bellinzona a Valli, Bellinzona, Switzerland.
Xavier CapdevilaCentre Hospitalier Universitaire de Montpellier, Montpellier, France.
Davide La ReginaOspedale Regionale di Bellinzona a Valli, Bellinzona, Switzerland.
Andrea SaporitoOspedale Regionale di Bellinzona a Valli, Bellinzona, Switzerland.
Ospedale Regionale di Bellinzona e Valli · CHUniversità della Svizzera italiana · CHCentre Hospitalier Universitaire de Montpellier · FROspedale regionale di Lugano · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesAnesthesiologists and hospitals are increasingly confronted with costs associated with the complications of Peripheral Nerve Blocks (PNB) procedures. The objective of our study was to identify the incidence of the main adverse events associated with regional anesthesia, particularly during anesthetic PNB, and to evaluate the associated healthcare and social costs.

methodsAccording to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, we conducted a systematic search on EMBASE and PubMed with the following search strategy: ("regional anesthesia" OR "nerve block") AND ("complications" OR "nerve lesion" OR "nerve damage" OR "nerve injury"). Studies on patients undergoing a regional anesthesia procedure other than spinal or epidural were included. Targeted data of the selected studies were extracted and further analyzed.

resultsLiterature search revealed 487 articles, 21 of which met the criteria to be included in our analysis. Ten of them were included in the qualitative and 11 articles in the quantitative synthesis. The analysis of costs included data from four studies and 2,034 claims over 51,242 cases. The median claim consisted in 39,524 dollars in the United States and 22,750 pounds in the United Kingdom. The analysis of incidence included data from seven studies involving 424,169 patients with an overall estimated incidence of 137/10,000.

conclusionsDespite limitations, we proposed a simple model of cost calculation. We found that, despite the relatively low incidence of adverse events following PNB, their associated costs were relevant and should be carefully considered by healthcare managers and decision makers.

Indexed as

Anesthesia, ConductionNerve BlockFinancial StressHumansUnited StatesComplaintsComplicationsCostsNerve injuryRegional anesthesia

Identifiers

PMID33823209
PMCPMC10240238
OpenAlexW3151211231

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.